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    1. - 01100 Metabolism
    1. - 01110 Carbohydrate Metabolism
    1. 00010 Glycolysis / Gluconeogenesis
    2. 00020 Citrate cycle (TCA cycle)
    3. 00030 Pentose phosphate pathway
    4. 00031 Inositol metabolism
    5. 00040 Pentose and glucuronate interconversions
    6. 00051 Fructose and mannose metabolism
    7. 00052 Galactose metabolism
    8. 00053 Ascorbate and aldarate metabolism
    9. 00500 Starch and sucrose metabolism
    10. 00520 Nucleotide sugars metabolism
    11. 00530 Aminosugars metabolism
    12. 00562 Inositol phosphate metabolism
    13. 00620 Pyruvate metabolism
    14. 00630 Glyoxylate and dicarboxylate metabolism
    15. 00640 Propanoate metabolism
    16. 00650 Butanoate metabolism
    17. 00660 C5-Branched dibasic acid metabolism
    1. - 01120 Energy Metabolism
    1. 00190 Oxidative phosphorylation
    2. 00195 Photosynthesis
    3. 00196 Photosynthesis - antenna proteins
    4. 00680 Methane metabolism
    5. 00710 Carbon fixation
    6. 00720 Reductive carboxylate cycle (CO2 fixation)
    7. 00910 Nitrogen metabolism
    8. 00920 Sulfur metabolism
    1. - 01130 Lipid Metabolism
    1. 00061 Fatty acid biosynthesis
    2. 00062 Fatty acid elongation in mitochondria
    3. 00071 Fatty acid metabolism
    4. 00072 Synthesis and degradation of ketone bodies
    5. 00100 Biosynthesis of steroids
    6. 00120 Bile acid biosynthesis
    7. 00140 C21-Steroid hormone metabolism
    8. 00150 Androgen and estrogen metabolism
    9. 00561 Glycerolipid metabolism
    10. 00564 Glycerophospholipid metabolism
    11. 00565 Ether lipid metabolism
    12. 00590 Arachidonic acid metabolism
    13. 00591 Linoleic acid metabolism
    14. 00592 alpha-Linolenic acid metabolism
    15. 00600 Sphingolipid metabolism
    16. 01040 Polyunsaturated fatty acid biosynthesis
    1. - 01140 Nucleotide Metabolism
    1. 00230 Purine metabolism
    2. 00240 Pyrimidine metabolism
    1. - 01150 Amino Acid Metabolism
    1. 00220 Urea cycle and metabolism of amino groups
    2. 00251 Glutamate metabolism
    3. 00252 Alanine and aspartate metabolism
    4. 00260 Glycine, serine and threonine metabolism
    5. 00271 Methionine metabolism
    6. 00272 Cysteine metabolism
    7. 00280 Valine, leucine and isoleucine degradation
    8. 00290 Valine, leucine and isoleucine biosynthesis
    9. 00300 Lysine biosynthesis
    10. 00310 Lysine degradation
    11. 00330 Arginine and proline metabolism
    12. 00340 Histidine metabolism
    13. 00350 Tyrosine metabolism
    14. 00360 Phenylalanine metabolism
    15. 00380 Tryptophan metabolism
    16. 00400 Phenylalanine, tyrosine and tryptophan biosynthesis
    1. - 01160 Metabolism of Other Amino Acids
    1. 00410 beta-Alanine metabolism
    2. 00430 Taurine and hypotaurine metabolism
    3. 00440 Aminophosphonate metabolism
    4. 00450 Selenoamino acid metabolism
    5. 00460 Cyanoamino acid metabolism
    6. 00471 D-Glutamine and D-glutamate metabolism
    7. 00472 D-Arginine and D-ornithine metabolism
    8. 00473 D-Alanine metabolism
    9. 00480 Glutathione metabolism
    1. - 01170 Glycan Biosynthesis and Metabolism
    1. 00510 N-Glycan biosynthesis
    2. 00511 N-Glycan degradation
    3. 00512 O-Glycan biosynthesis
    4. 00513 High-mannose type N-glycan biosynthesis
    5. 00531 Glycosaminoglycan degradation
    6. 00532 Chondroitin sulfate biosynthesis
    7. 00533 Keratan sulfate biosynthesis
    8. 00534 Heparan sulfate biosynthesis
    9. 00540 Lipopolysaccharide biosynthesis
    10. 00550 Peptidoglycan biosynthesis
    11. 00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
    12. 00601 Glycosphingolipid biosynthesis - lactoseries
    13. 00602 Glycosphingolipid biosynthesis - neo-lactoseries
    14. 00603 Glycosphingolipid biosynthesis - globoseries
    15. 00604 Glycosphingolipid biosynthesis - ganglioseries
    16. 01030 Glycan structures - biosynthesis 1
    17. 01031 Glycan structures - biosynthesis 2
    18. 01032 Glycan structures - degradation
    1. - 01190 Metabolism of Cofactors and Vitamins
    1. 00130 Ubiquinone biosynthesis
    2. 00670 One carbon pool by folate
    3. 00730 Thiamine metabolism
    4. 00740 Riboflavin metabolism
    5. 00750 Vitamin B6 metabolism
    6. 00760 Nicotinate and nicotinamide metabolism
    7. 00770 Pantothenate and CoA biosynthesis
    8. 00780 Biotin metabolism
    9. 00785 Lipoic acid metabolism
    10. 00790 Folate biosynthesis
    11. 00830 Retinol metabolism
    12. 00860 Porphyrin and chlorophyll metabolism
    1. - 01195 Biosynthesis of Secondary Metabolites
    1. 00231 Puromycin biosynthesis
    2. 00232 Caffeine metabolism
    3. 00253 Tetracycline biosynthesis
    4. 00311 Penicillin and cephalosporin biosynthesis
    5. 00312 beta-Lactam resistance
    6. 00331 Clavulanic acid biosynthesis
    7. 00401 Novobiocin biosynthesis
    8. 00402 Benzoxazinone biosynthesis
    9. 00521 Streptomycin biosynthesis
    10. 00900 Terpenoid biosynthesis
    11. 00901 Indole and ipecac alkaloid biosynthesis
    12. 00902 Monoterpenoid biosynthesis
    13. 00903 Limonene and pinene degradation
    14. 00904 Diterpenoid biosynthesis
    15. 00905 Brassinosteroid biosynthesis
    16. 00906 Carotenoid biosynthesis
    17. 00940 Phenylpropanoid biosynthesis
    18. 00941 Flavonoid biosynthesis
    19. 00942 Anthocyanin biosynthesis
    20. 00943 Isoflavonoid biosynthesis
    21. 00950 Alkaloid biosynthesis I
    22. 00960 Alkaloid biosynthesis II
    23. 01058 Acridone alkaloid biosynthesis
    1. - 01196 Xenobiotics Biodegradation and Metabolism
    1. 00351 1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane (DDT) degradation
    2. 00361 gamma-Hexachlorocyclohexane degradation
    3. 00362 Benzoate degradation via hydroxylation
    4. 00363 Bisphenol A degradation
    5. 00621 Biphenyl degradation
    6. 00622 Toluene and xylene degradation
    7. 00623 2,4-Dichlorobenzoate degradation
    8. 00624 1- and 2-Methylnaphthalene degradation
    9. 00625 Tetrachloroethene degradation
    10. 00626 Naphthalene and anthracene degradation
    11. 00627 1,4-Dichlorobenzene degradation
    12. 00628 Fluorene degradation
    13. 00629 Carbazole degradation
    14. 00631 1,2-Dichloroethane degradation
    15. 00632 Benzoate degradation via CoA ligation
    16. 00633 Trinitrotoluene degradation
    17. 00641 3-Chloroacrylic acid degradation
    18. 00642 Ethylbenzene degradation
    19. 00643 Note!Styrene degradation
    20. 00791 Atrazine degradation
    21. 00930 Caprolactam degradation
    22. 00980 Metabolism of xenobiotics by cytochrome P450
    1. - Biosynthesis of Polyketides and Nonribosomal Peptides
    1. 00522 Biosynthesis of 12-, 14- and 16-membered macrolides
    2. 00523 Polyketide sugar unit biosynthesis
    3. 01051 Biosynthesis of ansamycins
    4. 01052 Type I polyketide structures
    5. 01053 Biosynthesis of siderophore group nonribosomal peptides
    6. 01054 Nonribosomal peptide structures
    7. 01055 Biosynthesis of vancomycin group antibiotics
    8. 01056 Biosynthesis of type II polyketide backbone
    9. 01057 Biosynthesis of type II polyketide products
    1. - Genetic Information Processing
    1. - Transcription
    1. RNA biosynthesis
    2. 03020 RNA polymerase
    3. 03022 Basal transcription factors
    1. - Translation
    1. 00970 Aminoacyl-tRNA biosynthesis
    2. Protein biosynthesis
    3. 03010 Ribosome
    1. - Sorting and Degradation
    1. 03050 Proteasome
    2. 03060 Protein export
    3. 03070 Type III secretion system
    4. 03080 Type IV secretion system
    5. 03090 Type II secretion system
    6. 04120 Ubiquitin mediated proteolysis
    7. 04130 SNARE interactions in vesicular transport
    8. 04140 Regulation of autophagy
    1. - Replication and Repair
    1. 03030 DNA polymerase
    1. - Environmental Information Processing
    1. - Membrane Transport
    1. 02010 ABC transporters
    2. 02060 Phosphotransferase system (PTS)
    1. - Signal Transduction
    1. 02020 Two-component system
    2. 04010 MAPK signaling pathway
    3. 04012 ErbB signaling pathway
    4. 04020 Calcium signaling pathway
    5. 04070 Phosphatidylinositol signaling system
    6. 04150 mTOR signaling pathway
    7. 04310 Wnt signaling pathway
    8. 04330 Notch signaling pathway
    9. 04340 Hedgehog signaling pathway
    10. 04350 TGF-beta signaling pathway
    11. 04370 VEGF signaling pathway
    12. 04630 Jak-STAT signaling pathway
    1. - Signaling Molecules and Interaction
    1. 04060 Cytokine-cytokine receptor interaction
    2. 04080 Neuroactive ligand-receptor interaction
    3. 04512 ECM-receptor interaction
    4. 04514 Cell adhesion molecules (CAMs)
    1. - Cellular Processes
    1. - 01430 Cell Communication
    1. 04510 Focal adhesion
    2. 04520 Adherens junction
    3. 04530 Tight junction
    4. 04540 Gap junction
    1. - Cell Motility
    1. 02030 Bacterial chemotaxis
    2. 02040 Flagellar assembly
    3. 04810 Regulation of actin cytoskeleton
    1. - Cell Growth and Death
    1. 04110 Cell cycle
    2. 04111 Cell cycle - yeast
    3. 04115 p53 signaling pathway
    4. 04210 Apoptosis
    1. - Endocrine System
    1. 03320 PPAR signaling pathway
    2. 04614 Renin-angiotensin system
    3. 04910 Insulin signaling pathway
    4. 04912 GnRH signaling pathway
    5. 04914 Progesterone-mediated oocyte maturation
    6. 04916 Melanogenesis
    7. 04920 Adipocytokine signaling pathway
    1. - Immune System
    1. 04610 Complement and coagulation cascades
    2. 04612 Antigen processing and presentation
    3. 04620 Toll-like receptor signaling pathway
    4. 04640 Hematopoietic cell lineage
    5. 04650 Natural killer cell mediated cytotoxicity
    6. 04660 T cell receptor signaling pathway
    7. 04662 B cell receptor signaling pathway
    8. 04664 Fc epsilon RI signaling pathway
    9. 04670 Leukocyte transendothelial migration
    1. - Nervous System
    1. 04720 Long-term potentiation
    2. 04730 Long-term depression
    1. - Sensory System
    1. 04740 Olfactory transduction
    2. 04742 Taste transduction
    1. - Development
    1. 04320 Dorso-ventral axis formation
    2. 04360 Axon guidance
    1. - Behavior
    1. 04710 Circadian rhythm
    1. - Human Diseases
    1. - 01510 Neurodegenerative Diseases
    1. 05010 Alzheimer's disease
    2. 05020 Parkinson's disease
    3. 05030 Amyotrophic lateral sclerosis (ALS)
    4. 05040 Huntington's disease
    5. 05050 Dentatorubropallidoluysian atrophy (DRPLA)
    6. 05060 Prion disease
    1. - Cancers
    1. 05210 Colorectal cancer
    2. 05211 Renal cell carcinoma
    3. 05212 Pancreatic cancer
    4. 05213 Endometrial cancer
    5. 05214 Glioma
    6. 05215 Prostate cancer
    7. 05216 Thyroid cancer
    8. 05217 Basal cell carcinoma
    9. 05218 Melanoma
    10. 05219 Bladder cancer
    11. 05220 Chronic myeloid leukemia
    12. 05221 Acute myeloid leukemia
    13. 05222 Small cell lung cancer
    14. 05223 Non-small cell lung cancer
    1. - Metabolic Disorders
    1. 04930 Type II diabetes mellitus
    2. 04940 Type I diabetes mellitus
    3. 04950 Maturity onset diabetes of the young
    1. - Infectious Diseases
    1. 05110 Cholera
    2. 05120 Epithelial cell signaling in Helicobacter pylori infection
    3. 05130 Pathogenic Escherichia coli infection
    1. - Drug Development
    1. - Chronology: Antibiotics
    1. Penicillins
    2. Cephalosporins - parenteral agents
    3. Cephalosporins - oral agents
    4. Quinolones
    5. Tetracyclines
    6. Macrolides and ketolides
    7. Aminoglycosides - Streptomyces
    8. Aminoglycosides - Micromonospora
    9. Rifamycins
    1. - Chronology: Nervous System Agents
    1. Local analgesics
    2. Antidepressants
    3. Antipsychotics
    4. Antipsychotics - phenothiazines
    5. Anxiolytics
    6. Antipsychotics - butyrophenones
    7. Hypnotics
    8. Anticonvulsants
    9. Opioid analgesics
    1. - Chronology: Other Drugs
    1. Sulfonamide derivatives - sulfa drugs
    2. Sulfonamide derivatives - diuretics
    3. Sulfonamide derivatives - hypoglycemic agents
    4. Statins
    5. Quinolines
    6. Azoles
    7. Eicosanoids
    8. Prostaglandins
    9. Antiarrhythmic drugs
    10. Antacids
    11. Antineoplastics - alkylating agents
    12. Antineoplastics - antimetabolic agents
    13. Antineoplastics - agents from natural products
    14. Antineoplastics - hormones
    15. Antiviral
    16. Antineoplastics - protein kinases inhibitors
    17. Immunosuppressive agents
    1. - Target Based Structure Classification
    1. Calcium channel blocking agents
    2. Serotonin receptor antagonists/agonists
    3. Histamine receptor antagonists
    4. Dopamine receptor antagonists/agonists
    5. beta-Adrenergic receptor agonists/antagonists
    6. alpha-Adrenergic receptor agonists/antagonists
    7. Catecholamine transferase inhibitors
    8. Angiotensin antagonists
    9. HIV protease inhibitors
    10. Cyclooxygenase inhibitors
    1. - Skeleton Based Structure Classification
    1. Benzoic acid family
    2. 2-Aminothiazole family
    3. 1,2-Diphenyl substitution family
    4. Furan family
    5. Naphthalene family
    6. Sulfonamide family
    7. Butyrophenone family
    8. Benzodiazepine family