SIC: a tool to detect short inverted segments in a biological sequence

Robelin, D. and Richard, H. and Prum, B.

Nucl. Acids. Res. 31, 2003.


The web software SIC provides a tool to search for short inverted segments (length 3-5000 bp) in a DNA sequence. The sequence is assumed to follow a Markov model. A statistic which is sensitive to inversion is presented. Searching inverted segments is done by a scanning approach after the user specifies the size of the scanning window and the order of the Markov chain. A list of the highest score segments is given with an assessment of the randomness of the result. SIC can be accessed via the URL:

Key words and phrases

Statistiques des Séquences Biologiques Home Page