ID	1575712-10
sentence	sigma F activity in the forespore regulates the proteolytic processing of sigma E within the mother cell compartment.
words	word(0,'sigma F',0,6)	word(1,'activity',8,15)	word(2,'in',17,18)	word(3,'the',20,22)	word(4,'forespore',24,32)	word(5,'regulates',34,42)	word(6,'the',44,46)	word(7,'proteolytic',48,58)	word(8,'processing',60,69)	word(9,'of',71,72)	word(10,'sigma E',74,80)	word(11,'within',82,87)	word(12,'the',89,91)	word(13,'mother',93,98)	word(14,'cell',100,103)	word(15,'compartment',105,115)
agents	agent(0)
targets	target(10)
genic_interactions	genic_interaction(0,10)

ID	1900494-5
sentence	We also show that spoIVB transcription is partially dependent on the action of the mother cell regulatory gene spoIIID, a finding that suggests that the transcription of certain forespore-expressed genes is influenced by events in the mother cell.
words	word(0,'We',0,1)	word(1,'also',3,6)	word(2,'show',8,11)	word(3,'that',13,16)	word(4,'spoIVB',18,23)	word(5,'transcription',25,37)	word(6,'is',39,40)	word(7,'partially',42,50)	word(8,'dependent',52,60)	word(9,'on',62,63)	word(10,'the',65,67)	word(11,'action',69,74)	word(12,'of',76,77)	word(13,'the',79,81)	word(14,'mother',83,88)	word(15,'cell',90,93)	word(16,'regulatory',95,104)	word(17,'gene',106,109)	word(18,'spoIIID',111,117)	word(19,'a',120,120)	word(20,'finding',122,128)	word(21,'that',130,133)	word(22,'suggests',135,142)	word(23,'that',144,147)	word(24,'the',149,151)	word(25,'transcription',153,165)	word(26,'of',167,168)	word(27,'certain',170,176)	word(28,'forespore-expressed',178,196)	word(29,'genes',198,202)	word(30,'is',204,205)	word(31,'influenced',207,216)	word(32,'by',218,219)	word(33,'events',221,226)	word(34,'in',228,229)	word(35,'the',231,233)	word(36,'mother',235,240)	word(37,'cell',242,245)
agents	agent(18)
targets	target(4)
genic_interactions	genic_interaction(18,4)

ID	1900507-1
sentence	The sspB and sspE genes code for major small, acid-soluble proteins of Bacillus subtilis spores and are transcribed during sporulation by RNA polymerase containing sigma G.
words	word(0,'The',0,2)	word(1,'sspB',4,7)	word(2,'and',9,11)	word(3,'sspE',13,16)	word(4,'genes',18,22)	word(5,'code',24,27)	word(6,'for',29,31)	word(7,'major',33,37)	word(8,'small',39,43)	word(9,'acid-soluble',46,57)	word(10,'proteins',59,66)	word(11,'of',68,69)	word(12,'Bacillus',71,78)	word(13,'subtilis',80,87)	word(14,'spores',89,94)	word(15,'and',96,98)	word(16,'are',100,102)	word(17,'transcribed',104,114)	word(18,'during',116,121)	word(19,'sporulation',123,133)	word(20,'by',135,136)	word(21,'RNA',138,140)	word(22,'polymerase',142,151)	word(23,'containing',153,162)	word(24,'sigma G',164,170)
agents	agent(24)
targets	target(1)	target(3)
genic_interactions	genic_interaction(24,1)	genic_interaction(24,3)

ID	1902213-7
sentence	These data suggest that synthesis of sigma G is dependent neither on transcription from the spoIIG promoter nor on sigma G itself but can be due to another transcription factor.
words	word(0,'These',0,4)	word(1,'data',6,9)	word(2,'suggest',11,17)	word(3,'that',19,22)	word(4,'synthesis',24,32)	word(5,'of',34,35)	word(6,'sigma G',37,43)	word(7,'is',45,46)	word(8,'dependent',48,56)	word(9,'neither',58,64)	word(10,'on',66,67)	word(11,'transcription',69,81)	word(12,'from',83,86)	word(13,'the',88,90)	word(14,'spoIIG',92,97)	word(15,'promoter',99,106)	word(16,'nor',108,110)	word(17,'on',112,113)	word(18,'sigma G',115,121)	word(19,'itself',123,128)	word(20,'but',130,132)	word(21,'can',134,136)	word(22,'be',138,139)	word(23,'due',141,143)	word(24,'to',145,146)	word(25,'another',148,154)	word(26,'transcription',156,168)	word(27,'factor',170,175)
agents	agent(14)	agent(18)
targets	target(6)
genic_interactions	genic_interaction(14,6)	genic_interaction(18,6)

ID	1905664-3
sentence	We found that sigma H-RNA polymerase transcribes spoIIA accurately in vitro and propose that sigma H directs transcription of spoIIA during sporulation.
words	word(0,'We',0,1)	word(1,'found',3,7)	word(2,'that',9,12)	word(3,'sigma H',14,20)	word(4,'RNA',22,24)	word(5,'polymerase',26,35)	word(6,'transcribes',37,47)	word(7,'spoIIA',49,54)	word(8,'accurately',56,65)	word(9,'in',67,68)	word(10,'vitro',70,74)	word(11,'and',76,78)	word(12,'propose',80,86)	word(13,'that',88,91)	word(14,'sigma H',93,99)	word(15,'directs',101,107)	word(16,'transcription',109,121)	word(17,'of',123,124)	word(18,'spoIIA',126,131)	word(19,'during',133,138)	word(20,'sporulation',140,150)
agents	agent(3)	agent(14)
targets	target(7)	target(18)
genic_interactions	genic_interaction(3,7)	genic_interaction(14,18)

ID	1938874-8
sentence	These observations confirm that spoIIAB is essential for sporulation and are consistent with models in which the product of spoIIAB plays a role in regulating the timing and/or compartment specificity of sigma F- and sigma G-directed transcription.
words	word(0,'These',0,4)	word(1,'observations',6,17)	word(2,'confirm',19,25)	word(3,'that',27,30)	word(4,'spoIIAB',32,38)	word(5,'is',40,41)	word(6,'essential',43,51)	word(7,'for',53,55)	word(8,'sporulation',57,67)	word(9,'and',69,71)	word(10,'are',73,75)	word(11,'consistent',77,86)	word(12,'with',88,91)	word(13,'models',93,98)	word(14,'in',100,101)	word(15,'which',103,107)	word(16,'the',109,111)	word(17,'product',113,119)	word(18,'of',121,122)	word(19,'spoIIAB',124,130)	word(20,'plays',132,136)	word(21,'a',138,138)	word(22,'role',140,143)	word(23,'in',145,146)	word(24,'regulating',148,157)	word(25,'the',159,161)	word(26,'timing',163,168)	word(27,'and/or',170,175)	word(28,'compartment',177,187)	word(29,'specificity',189,199)	word(30,'of',201,202)	word(31,'sigma F',204,210)	word(32,'and',213,215)	word(33,'sigma G',217,223)	word(34,'directed',225,232)	word(35,'transcription',234,246)
agents	agent(19)
targets	target(31)	target(33)
genic_interactions	genic_interaction(19,31)	genic_interaction(19,33)

ID	2492118-2
sentence	A 27-kilodalton RNA polymerase sigma factor called sigma K (or sigma 27) has been found that causes weak transcription of spoIVCB and strong transcription of cotD.
words	word(0,'A',0,0)	word(1,'27-kilodalton',2,14)	word(2,'RNA',16,18)	word(3,'polymerase',20,29)	word(4,'sigma',31,35)	word(5,'factor',37,42)	word(6,'called',44,49)	word(7,'sigma K',51,57)	word(8,'or',60,61)	word(9,'sigma',63,67)	word(10,'27',69,70)	word(11,'has',73,75)	word(12,'been',77,80)	word(13,'found',82,86)	word(14,'that',88,91)	word(15,'causes',93,98)	word(16,'weak',100,103)	word(17,'transcription',105,117)	word(18,'of',119,120)	word(19,'spoIVCB',122,128)	word(20,'and',130,132)	word(21,'strong',134,139)	word(22,'transcription',141,153)	word(23,'of',155,156)	word(24,'cotD',158,161)
agents	agent(7)
targets	target(19)	target(24)
genic_interactions	genic_interaction(7,19)	genic_interaction(7,24)

ID	2500529-2
sentence	The product of regulatory gene spo0H is an RNA polymerase sigma factor called sigma H, which directs transcription of a sporulation gene known as spoVG.
words	word(0,'The',0,2)	word(1,'product',4,10)	word(2,'of',12,13)	word(3,'regulatory',15,24)	word(4,'gene',26,29)	word(5,'spo0H',31,35)	word(6,'is',37,38)	word(7,'an',40,41)	word(8,'RNA',43,45)	word(9,'polymerase',47,56)	word(10,'sigma',58,62)	word(11,'factor',64,69)	word(12,'called',71,76)	word(13,'sigma H',78,84)	word(14,'which',87,91)	word(15,'directs',93,99)	word(16,'transcription',101,113)	word(17,'of',115,116)	word(18,'a',118,118)	word(19,'sporulation',120,130)	word(20,'gene',132,135)	word(21,'known',137,141)	word(22,'as',143,144)	word(23,'spoVG',146,150)
agents	agent(13)
targets	target(23)
genic_interactions	genic_interaction(13,23)

ID	2512576-6
sentence	These results support a model in which a form of RNA polymerase containing sigma A is utilized in an unusual manner to activate the transcription of the spoIIG operon well after the onset of endospore formation.
words	word(0,'These',0,4)	word(1,'results',6,12)	word(2,'support',14,20)	word(3,'a',22,22)	word(4,'model',24,28)	word(5,'in',30,31)	word(6,'which',33,37)	word(7,'a',39,39)	word(8,'form',41,44)	word(9,'of',46,47)	word(10,'RNA',49,51)	word(11,'polymerase',53,62)	word(12,'containing',64,73)	word(13,'sigma A',75,81)	word(14,'is',83,84)	word(15,'utilized',86,93)	word(16,'in',95,96)	word(17,'an',98,99)	word(18,'unusual',101,107)	word(19,'manner',109,114)	word(20,'to',116,117)	word(21,'activate',119,126)	word(22,'the',128,130)	word(23,'transcription',132,144)	word(24,'of',146,147)	word(25,'the',149,151)	word(26,'spoIIG',153,158)	word(27,'operon',160,165)	word(28,'well',167,170)	word(29,'after',172,176)	word(30,'the',178,180)	word(31,'onset',182,186)	word(32,'of',188,189)	word(33,'endospore',191,199)	word(34,'formation',201,209)
agents	agent(13)
targets	target(26)
genic_interactions	genic_interaction(13,26)

ID	7570023-2
sentence	The activity of sigma F is governed by SpoIIAA, SpoIIAB, and SpoIIE, a membrane protein localized at the polar septum.
words	word(0,'The',0,2)	word(1,'activity',4,11)	word(2,'of',13,14)	word(3,'sigma F',16,22)	word(4,'is',24,25)	word(5,'governed',27,34)	word(6,'by',36,37)	word(7,'SpoIIAA',39,45)	word(8,'SpoIIAB',48,54)	word(9,'and',57,59)	word(10,'SpoIIE',61,66)	word(11,'a',69,69)	word(12,'membrane',71,78)	word(13,'protein',80,86)	word(14,'localized',88,96)	word(15,'at',98,99)	word(16,'the',101,103)	word(17,'polar',105,109)	word(18,'septum',111,116)
agents	agent(7)	agent(8)	agent(10)
targets	target(3)
genic_interactions	genic_interaction(7,3)	genic_interaction(8,3)	genic_interaction(10,3)

ID	7642514-1
sentence	Activation of pro-sigma K processing in the mother cell at late stages of sporulation in Bacillus subtilis requires the presence of active sigma G in the forespore.
words	word(0,'Activation',0,9)	word(1,'of',11,12)	word(2,'pro-sigma K',14,24)	word(3,'processing',26,35)	word(4,'in',37,38)	word(5,'the',40,42)	word(6,'mother',44,49)	word(7,'cell',51,54)	word(8,'at',56,57)	word(9,'late',59,62)	word(10,'stages',64,69)	word(11,'of',71,72)	word(12,'sporulation',74,84)	word(13,'in',86,87)	word(14,'Bacillus',89,96)	word(15,'subtilis',98,105)	word(16,'requires',107,114)	word(17,'the',116,118)	word(18,'presence',120,127)	word(19,'of',129,130)	word(20,'active',132,137)	word(21,'sigma G',139,145)	word(22,'in',147,148)	word(23,'the',150,152)	word(24,'forespore',154,162)
agents	agent(21)
targets	target(2)
genic_interactions	genic_interaction(21,2)

ID	7768864-10
sentence	Analysis of RNA isolated from a sigma B deletion mutant revealed that the transcription of gspA is sigma B dependent.
words	word(0,'Analysis',0,7)	word(1,'of',9,10)	word(2,'RNA',12,14)	word(3,'isolated',16,23)	word(4,'from',25,28)	word(5,'a',30,30)	word(6,'sigma B',32,38)	word(7,'deletion',40,47)	word(8,'mutant',49,54)	word(9,'revealed',56,63)	word(10,'that',65,68)	word(11,'the',70,72)	word(12,'transcription',74,86)	word(13,'of',88,89)	word(14,'gspA',91,94)	word(15,'is',96,97)	word(16,'sigma B',99,105)	word(17,'dependent',107,115)
agents	agent(16)
targets	target(14)
genic_interactions	genic_interaction(16,14)

ID	7814326-6
sentence	Like the promoter for cotB, the cotG promoter is induced at a late stage of sporulation under the control of the RNA polymerase sigma factor sigma K and the DNA-binding protein GerE.
words	word(0,'Like',0,3)	word(1,'the',5,7)	word(2,'promoter',9,16)	word(3,'for',18,20)	word(4,'cotB',22,25)	word(5,'the',28,30)	word(6,'cotG',32,35)	word(7,'promoter',37,44)	word(8,'is',46,47)	word(9,'induced',49,55)	word(10,'at',57,58)	word(11,'a',60,60)	word(12,'late',62,65)	word(13,'stage',67,71)	word(14,'of',73,74)	word(15,'sporulation',76,86)	word(16,'under',88,92)	word(17,'the',94,96)	word(18,'control',98,104)	word(19,'of',106,107)	word(20,'the',109,111)	word(21,'RNA',113,115)	word(22,'polymerase',117,126)	word(23,'sigma',128,132)	word(24,'factor',134,139)	word(25,'sigma K',141,147)	word(26,'and',149,151)	word(27,'the',153,155)	word(28,'DNA-binding',157,167)	word(29,'protein',169,175)	word(30,'GerE',177,180)
agents	agent(25)	agent(30)
targets	target(6)	target(4)
genic_interactions	genic_interaction(25,6)	genic_interaction(30,6)	genic_interaction(25,4)	genic_interaction(30,4)

ID	7883171-2
sentence	Activation of sigma E depends on sigma F, the factor that governs transcription in the forespore.
words	word(0,'Activation',0,9)	word(1,'of',11,12)	word(2,'sigma E',14,20)	word(3,'depends',22,28)	word(4,'on',30,31)	word(5,'sigma F',33,39)	word(6,'the',42,44)	word(7,'factor',46,51)	word(8,'that',53,56)	word(9,'governs',58,64)	word(10,'transcription',66,78)	word(11,'in',80,81)	word(12,'the',83,85)	word(13,'forespore',87,95)
agents	agent(5)
targets	target(2)
genic_interactions	genic_interaction(5,2)

ID	7896717-1
sentence	SpoIIID is a sequence-specific, DNA-binding protein that activates or represses transcription of different genes by sigma K RNA polymerase in vitro.
words	word(0,'SpoIIID',0,6)	word(1,'is',8,9)	word(2,'a',11,11)	word(3,'sequence-specific',13,29)	word(4,'DNA-binding',32,42)	word(5,'protein',44,50)	word(6,'that',52,55)	word(7,'activates',57,65)	word(8,'or',67,68)	word(9,'represses',70,78)	word(10,'transcription',80,92)	word(11,'of',94,95)	word(12,'different',97,105)	word(13,'genes',107,111)	word(14,'by',113,114)	word(15,'sigma K',116,122)	word(16,'RNA',124,126)	word(17,'polymerase',128,137)	word(18,'in',139,140)	word(19,'vitro',142,146)
agents	agent(0)
targets	target(15)
genic_interactions	genic_interaction(0,15)	genic_interaction(0,15)

ID	8093697-3
sentence	Primer extension analysis suggested that the cwlB operon is transcribed by E sigma D and E sigma A, the former transcripts being predominants at the exponential growth phase.
words	word(0,'Primer',0,5)	word(1,'extension',7,15)	word(2,'analysis',17,24)	word(3,'suggested',26,34)	word(4,'that',36,39)	word(5,'the',41,43)	word(6,'cwlB',45,48)	word(7,'operon',50,55)	word(8,'is',57,58)	word(9,'transcribed',60,70)	word(10,'by',72,73)	word(11,'E sigma D',75,83)	word(12,'and',85,87)	word(13,'E sigma A',89,97)	word(14,'the',100,102)	word(15,'former',104,109)	word(16,'transcripts',111,121)	word(17,'being',123,127)	word(18,'predominants',129,140)	word(19,'at',142,143)	word(20,'the',145,147)	word(21,'exponential',149,159)	word(22,'growth',161,166)	word(23,'phase',168,172)
agents	agent(11)	agent(13)
targets	target(6)
genic_interactions	genic_interaction(11,6)	genic_interaction(13,6)

ID	8231806-2
sentence	In vivo expression of the spoIIG promoter is activated shortly after the onset of sporulation and is dependent on kinA, spo0F, spo0B and spo0A genes.
words	word(0,'In',0,1)	word(1,'vivo',3,6)	word(2,'expression',8,17)	word(3,'of',19,20)	word(4,'the',22,24)	word(5,'spoIIG',26,31)	word(6,'promoter',33,40)	word(7,'is',42,43)	word(8,'activated',45,53)	word(9,'shortly',55,61)	word(10,'after',63,67)	word(11,'the',69,71)	word(12,'onset',73,77)	word(13,'of',79,80)	word(14,'sporulation',82,92)	word(15,'and',94,96)	word(16,'is',98,99)	word(17,'dependent',101,109)	word(18,'on',111,112)	word(19,'kinA',114,117)	word(20,'spo0F',120,124)	word(21,'spo0B',127,131)	word(22,'and',133,135)	word(23,'spo0A',137,141)	word(24,'genes',143,147)
agents	agent(19)	agent(20)	agent(21)	agent(23)
targets	target(5)
genic_interactions	genic_interaction(19,5)	genic_interaction(20,5)	genic_interaction(21,5)	genic_interaction(23,5)

ID	8320224-8
sentence	These results indicate that spoVE expression in sporulating cells is controlled essentially by sigma E-associated RNA polymerase.
words	word(0,'These',0,4)	word(1,'results',6,12)	word(2,'indicate',14,21)	word(3,'that',23,26)	word(4,'spoVE',28,32)	word(5,'expression',34,43)	word(6,'in',45,46)	word(7,'sporulating',48,58)	word(8,'cells',60,64)	word(9,'is',66,67)	word(10,'controlled',69,78)	word(11,'essentially',80,90)	word(12,'by',92,93)	word(13,'sigma E',95,101)	word(14,'associated',103,112)	word(15,'RNA',114,116)	word(16,'polymerase',118,127)
agents	agent(13)
targets	target(4)
genic_interactions	genic_interaction(13,4)

ID	8460143-9
sentence	RsbW efficiently blocked sigma B-dependent transcription but only if it was incubated with sigma B prior to the addition of the core enzyme.
words	word(0,'RsbW',0,3)	word(1,'efficiently',5,15)	word(2,'blocked',17,23)	word(3,'sigma B',25,31)	word(4,'dependent',33,41)	word(5,'transcription',43,55)	word(6,'but',57,59)	word(7,'only',61,64)	word(8,'if',66,67)	word(9,'it',69,70)	word(10,'was',72,74)	word(11,'incubated',76,84)	word(12,'with',86,89)	word(13,'sigma B',91,97)	word(14,'prior',99,103)	word(15,'to',105,106)	word(16,'the',108,110)	word(17,'addition',112,119)	word(18,'of',121,122)	word(19,'the',124,126)	word(20,'core',128,131)	word(21,'enzyme',133,138)
agents	agent(0)
targets	target(3)
genic_interactions	genic_interaction(0,3)

ID	8631668-3
sentence	Activation of sigma E requires expression of the sigma F-directed gene spoIIR.
words	word(0,'Activation',0,9)	word(1,'of',11,12)	word(2,'sigma E',14,20)	word(3,'requires',22,29)	word(4,'expression',31,40)	word(5,'of',42,43)	word(6,'the',45,47)	word(7,'sigma F',49,55)	word(8,'directed',57,64)	word(9,'gene',66,69)	word(10,'spoIIR',71,76)
agents	agent(10)	agent(7)
targets	target(2)	target(10)
genic_interactions	genic_interaction(10,2)	genic_interaction(7,10)

