9 __NODE__ __NODE__ in cell culture increases binding of promoter fragment ( 496 230 ) containing a PPRE from __SP__ Me gene(s) in mutant cells with a homozygous knockout of __SP__ __NODE__ and __SP__ __NODE__ and homodimeric __SP__ __NODE__(s) in mutant cells with a homozygous knockout of __SP__ __NODE__ and __SP__ __NODE__ .