Validation pour Ingenuity005

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Ingenuity005

precedent - 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 - suivant

Phrase 18 - PMID ?

Activation of SP NODE protein decreases differentiation of monocytes to activated macrophages .

Non annotée
Je ne sais pas
Je n'ai pas trouvé d'analyse satisfaisante

Commentaires :

Analyse 0

      +--------------SUBJ:V-N--------------+                                                            
      +--------COMP:N-N(of)-------+        |                                                            
      |           +-MOD_ATT:N-ADJ-+        +--------------------COMP:V-N(to)--------------------+       
      |           |       +MOD_ATT+        +---OBJ:V-N--+--COMP:N-N(of)-+            +MOD_ATT:N-+       
      |           |       |       |        |            |               |            |          |       
 Activation of __SP__ __NODE__ protein decreases differentiation of monocytes to activated macrophages .
COMP:N-N(of) (activation,protein)
MOD_ATT:N-ADJ (protein,__SP__)
MOD_ATT:N-ADJ (protein,__NODE__)
SUBJ:V-N (decrease,activation)
OBJ:V-N (decrease,differentiation)
COMP:V-N(to) (decrease,macrophage)
COMP:N-N(of) (differentiation,monocyte)
MOD_ATT:N-ADJ (macrophage,activate)

Analyse 1

      +--------------SUBJ:V-N--------------+                                                            
      +--------COMP:N-N(of)-------+        |                                                            
      |           +-MOD_ATT:N-ADJ-+        |                            +------COMP:N-N(to)-----+       
      |           |       +MOD_ATT+        +---OBJ:V-N--+--COMP:N-N(of)-+            +MOD_ATT:N-+       
      |           |       |       |        |            |               |            |          |       
 Activation of __SP__ __NODE__ protein decreases differentiation of monocytes to activated macrophages .
COMP:N-N(of) (activation,protein)
MOD_ATT:N-ADJ (protein,__SP__)
MOD_ATT:N-ADJ (protein,__NODE__)
SUBJ:V-N (decrease,activation)
OBJ:V-N (decrease,differentiation)
COMP:N-N(of) (differentiation,monocyte)
COMP:N-N(to) (monocyte,macrophage)
MOD_ATT:N-ADJ (macrophage,activate)

Analyse 2

      +--------------SUBJ:V-N--------------+                                                            
      +--------COMP:N-N(of)-------+        |                                                            
      |           +-MOD_ATT:N-ADJ-+        |            +--------------COMP:N-N(to)-------------+       
      |           |       +MOD_ATT+        +---OBJ:V-N--+--COMP:N-N(of)-+            +MOD_ATT:N-+       
      |           |       |       |        |            |               |            |          |       
 Activation of __SP__ __NODE__ protein decreases differentiation of monocytes to activated macrophages .
COMP:N-N(of) (activation,protein)
MOD_ATT:N-ADJ (protein,__SP__)
MOD_ATT:N-ADJ (protein,__NODE__)
SUBJ:V-N (decrease,activation)
OBJ:V-N (decrease,differentiation)
COMP:N-N(of) (differentiation,monocyte)
COMP:N-N(to) (differentiation,macrophage)
MOD_ATT:N-ADJ (macrophage,activate)

Analyse 3

      +-----------------------------SUBJ:V-N----------------------------+                               
      +----COMP:N-N(of)---+-----OBJ:V-N----+                            +------COMP:V-N(to)-----+       
      |           +MOD_ATT+       +SUBJ:V-N+---OBJ:V-N--+MOD_POST:+     |            +MOD_ATT:N-+       
      |           |       |       |        |            |         |     |            |          |       
 Activation of __SP__ __NODE__ protein decreases differentiation of monocytes to activated macrophages .
COMP:N-N(of) (activation,__NODE__)
MOD_ATT:N-ADJ (__NODE__,__SP__)
OBJ:V-N (decrease,__NODE__)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,differentiation)
MOD_POST:N-ADJ (differentiation,of)
SUBJ:V-N (monocyte,activation)
COMP:V-N(to) (monocyte,macrophage)
MOD_ATT:N-ADJ (macrophage,activate)

Analyse 4

      +-----------------------------SUBJ:V-N----------------------------+                               
      |           +---------OBJ:V-N--------+                            +------COMP:V-N(to)-----+       
      +COMP:N-N(of+       +MOD_ATT+SUBJ:V-N+---OBJ:V-N--+MOD_POST:+     |            +MOD_ATT:N-+       
      |           |       |       |        |            |         |     |            |          |       
 Activation of __SP__ __NODE__ protein decreases differentiation of monocytes to activated macrophages .
COMP:N-N(of) (activation,__SP__)
MOD_ATT:N-ADJ (protein,__NODE__)
OBJ:V-N (decrease,__SP__)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,differentiation)
MOD_POST:N-ADJ (differentiation,of)
SUBJ:V-N (monocyte,activation)
COMP:V-N(to) (monocyte,macrophage)
MOD_ATT:N-ADJ (macrophage,activate)

Analyse 5

      +-----------------------------SUBJ:V-N----------------------------+                               
      +---------------OBJ:V-N--------------+                            +------COMP:V-N(to)-----+       
      +COMP:N-N(of+       +MOD_ATT+SUBJ:V-N+---OBJ:V-N--+MOD_POST:+     |            +MOD_ATT:N-+       
      |           |       |       |        |            |         |     |            |          |       
 Activation of __SP__ __NODE__ protein decreases differentiation of monocytes to activated macrophages .
COMP:N-N(of) (activation,__SP__)
MOD_ATT:N-ADJ (protein,__NODE__)
OBJ:V-N (decrease,activation)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,differentiation)
MOD_POST:N-ADJ (differentiation,of)
SUBJ:V-N (monocyte,activation)
COMP:V-N(to) (monocyte,macrophage)
MOD_ATT:N-ADJ (macrophage,activate)

Analyse 6

      +-----------------------------SUBJ:V-N----------------------------+                               
      +---------------OBJ:V-N--------------+                            |                               
      +----COMP:N-N(of)---+                |                            +------COMP:V-N(to)-----+       
      |           +MOD_ATT+       +SUBJ:V-N+---OBJ:V-N--+MOD_POST:+     |            +MOD_ATT:N-+       
      |           |       |       |        |            |         |     |            |          |       
 Activation of __SP__ __NODE__ protein decreases differentiation of monocytes to activated macrophages .
COMP:N-N(of) (activation,__NODE__)
MOD_ATT:N-ADJ (__NODE__,__SP__)
OBJ:V-N (decrease,activation)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,differentiation)
MOD_POST:N-ADJ (differentiation,of)
SUBJ:V-N (monocyte,activation)
COMP:V-N(to) (monocyte,macrophage)
MOD_ATT:N-ADJ (macrophage,activate)

Analyse 7

      +-----------------------------------SUBJ:V-N-----------------------------------+                  
      +----COMP:N-N(of)---+-----OBJ:V-N----+-------------MOD:V-ADV-------------+     |                  
      |           +MOD_ATT+       +SUBJ:V-N+---OBJ:V-N--+--COMP:N-N(of)-+      |     +--OBJ:V-N-+       
      |           |       |       |        |            |               |      |     |          |       
 Activation of __SP__ __NODE__ protein decreases differentiation of monocytes to activated macrophages .
COMP:N-N(of) (activation,__NODE__)
MOD_ATT:N-ADJ (__NODE__,__SP__)
OBJ:V-N (decrease,__NODE__)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,differentiation)
MOD:V-ADV (decrease,to)
COMP:N-N(of) (differentiation,monocyte)
SUBJ:V-N (activate,activation)
OBJ:V-N (activate,macrophage)

Analyse 8

      +-----------------------------------SUBJ:V-N-----------------------------------+                  
      |           +---------OBJ:V-N--------+-------------MOD:V-ADV-------------+     |                  
      +COMP:N-N(of+       +MOD_ATT+SUBJ:V-N+---OBJ:V-N--+--COMP:N-N(of)-+      |     +--OBJ:V-N-+       
      |           |       |       |        |            |               |      |     |          |       
 Activation of __SP__ __NODE__ protein decreases differentiation of monocytes to activated macrophages .
COMP:N-N(of) (activation,__SP__)
MOD_ATT:N-ADJ (protein,__NODE__)
OBJ:V-N (decrease,__SP__)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,differentiation)
MOD:V-ADV (decrease,to)
COMP:N-N(of) (differentiation,monocyte)
SUBJ:V-N (activate,activation)
OBJ:V-N (activate,macrophage)

Analyse 9

      +-----------------------------------SUBJ:V-N-----------------------------------+                  
      +---------------OBJ:V-N--------------+-------------MOD:V-ADV-------------+     |                  
      +COMP:N-N(of+       +MOD_ATT+SUBJ:V-N+---OBJ:V-N--+--COMP:N-N(of)-+      |     +--OBJ:V-N-+       
      |           |       |       |        |            |               |      |     |          |       
 Activation of __SP__ __NODE__ protein decreases differentiation of monocytes to activated macrophages .
COMP:N-N(of) (activation,__SP__)
MOD_ATT:N-ADJ (protein,__NODE__)
OBJ:V-N (decrease,activation)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,differentiation)
MOD:V-ADV (decrease,to)
COMP:N-N(of) (differentiation,monocyte)
SUBJ:V-N (activate,activation)
OBJ:V-N (activate,macrophage)

Analyse 10

      +-----------------------------------SUBJ:V-N-----------------------------------+                  
      +---------------OBJ:V-N--------------+                                         |                  
      +----COMP:N-N(of)---+                +-------------MOD:V-ADV-------------+     |                  
      |           +MOD_ATT+       +SUBJ:V-N+---OBJ:V-N--+--COMP:N-N(of)-+      |     +--OBJ:V-N-+       
      |           |       |       |        |            |               |      |     |          |       
 Activation of __SP__ __NODE__ protein decreases differentiation of monocytes to activated macrophages .
COMP:N-N(of) (activation,__NODE__)
MOD_ATT:N-ADJ (__NODE__,__SP__)
OBJ:V-N (decrease,activation)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,differentiation)
MOD:V-ADV (decrease,to)
COMP:N-N(of) (differentiation,monocyte)
SUBJ:V-N (activate,activation)
OBJ:V-N (activate,macrophage)

Analyse 11

      +-----------------------------------------SUBJ:V-N----------------------------------------+       
      +---------------------------------SUBJ:V_PASS-N--------------------------------+          |       
      +----COMP:N-N(of)---+-----OBJ:V-N----+-------------MOD:V-ADV-------------+     |          |       
      |           +MOD_ATT+       +SUBJ:V-N+---OBJ:V-N--+--COMP:N-N(of)-+      |     |          |       
      |           |       |       |        |            |               |      |     |          |       
 Activation of __SP__ __NODE__ protein decreases differentiation of monocytes to activated macrophages .
COMP:N-N(of) (activation,__NODE__)
MOD_ATT:N-ADJ (__NODE__,__SP__)
OBJ:V-N (decrease,__NODE__)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,differentiation)
MOD:V-ADV (decrease,to)
COMP:N-N(of) (differentiation,monocyte)
SUBJ:V_PASS-N (activate,activation)
SUBJ:V-N (macrophage,activation)

Analyse 12

      +-----------------------------------------SUBJ:V-N----------------------------------------+       
      +---------------------------------SUBJ:V_PASS-N--------------------------------+          |       
      |           +---------OBJ:V-N--------+-------------MOD:V-ADV-------------+     |          |       
      +COMP:N-N(of+       +MOD_ATT+SUBJ:V-N+---OBJ:V-N--+--COMP:N-N(of)-+      |     |          |       
      |           |       |       |        |            |               |      |     |          |       
 Activation of __SP__ __NODE__ protein decreases differentiation of monocytes to activated macrophages .
COMP:N-N(of) (activation,__SP__)
MOD_ATT:N-ADJ (protein,__NODE__)
OBJ:V-N (decrease,__SP__)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,differentiation)
MOD:V-ADV (decrease,to)
COMP:N-N(of) (differentiation,monocyte)
SUBJ:V_PASS-N (activate,activation)
SUBJ:V-N (macrophage,activation)

Analyse 13

      +-----------------------------------SUBJ:V-N-----------------------------------+                  
      |           +-----------------------OBJ:V-N-----------------------+            |                  
      |           |       +-------------------SUBJ:V-N------------------+            |                  
      |           |       +-----OBJ:V-N----+                            |            |                  
      +COMP:N-N(of+       |       +SUBJ:V-N+---OBJ:V-N--+MOD_POST:+     +MOD:V-+     +--OBJ:V-N-+       
      |           |       |       |        |            |         |     |      |     |          |       
 Activation of __SP__ __NODE__ protein decreases differentiation of monocytes to activated macrophages .
COMP:N-N(of) (activation,__SP__)
OBJ:V-N (decrease,__NODE__)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,differentiation)
MOD_POST:N-ADJ (differentiation,of)
OBJ:V-N (monocyte,__SP__)
SUBJ:V-N (monocyte,__NODE__)
MOD:V-ADV (monocyte,to)
SUBJ:V-N (activate,activation)
OBJ:V-N (activate,macrophage)

Analyse 14

      +-----------------------------------SUBJ:V-N-----------------------------------+                  
      +-----------------------------OBJ:V-N-----------------------------+            |                  
      |                   +-------------------SUBJ:V-N------------------+            |                  
      |                   +-----OBJ:V-N----+                            |            |                  
      +COMP:N-N(of+       |       +SUBJ:V-N+---OBJ:V-N--+MOD_POST:+     +MOD:V-+     +--OBJ:V-N-+       
      |           |       |       |        |            |         |     |      |     |          |       
 Activation of __SP__ __NODE__ protein decreases differentiation of monocytes to activated macrophages .
COMP:N-N(of) (activation,__SP__)
OBJ:V-N (decrease,__NODE__)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,differentiation)
MOD_POST:N-ADJ (differentiation,of)
OBJ:V-N (monocyte,activation)
SUBJ:V-N (monocyte,__NODE__)
MOD:V-ADV (monocyte,to)
SUBJ:V-N (activate,activation)
OBJ:V-N (activate,macrophage)

Analyse 15

      +-----------------------------------------SUBJ:V-N----------------------------------------+       
      |           +------------------------------OBJ:V-N-----------------------------+          |       
      |           |       +-------------------------SUBJ:V-N-------------------------+          |       
      |           |       +-----OBJ:V-N----+-------------MOD:V-ADV-------------+     |          |       
      +COMP:N-N(of+       |       +SUBJ:V-N+---OBJ:V-N--+--COMP:N-N(of)-+      |     |          |       
      |           |       |       |        |            |               |      |     |          |       
 Activation of __SP__ __NODE__ protein decreases differentiation of monocytes to activated macrophages .
COMP:N-N(of) (activation,__SP__)
OBJ:V-N (decrease,__NODE__)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,differentiation)
MOD:V-ADV (decrease,to)
COMP:N-N(of) (differentiation,monocyte)
OBJ:V-N (activate,__SP__)
SUBJ:V-N (activate,__NODE__)
SUBJ:V-N (macrophage,activation)

Analyse 16

      +-----------------------------------------SUBJ:V-N----------------------------------------+       
      +---------------------------------SUBJ:V_PASS-N--------------------------------+          |       
      |           +-----------------------OBJ:V-N-----------------------+            |          |       
      |           |       +-------------------SUBJ:V-N------------------+            |          |       
      |           |       +-----OBJ:V-N----+                            |            |          |       
      +COMP:N-N(of+       |       +SUBJ:V-N+---OBJ:V-N--+MOD_POST:+     +MOD:V-+     |          |       
      |           |       |       |        |            |         |     |      |     |          |       
 Activation of __SP__ __NODE__ protein decreases differentiation of monocytes to activated macrophages .
COMP:N-N(of) (activation,__SP__)
OBJ:V-N (decrease,__NODE__)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,differentiation)
MOD_POST:N-ADJ (differentiation,of)
OBJ:V-N (monocyte,__SP__)
SUBJ:V-N (monocyte,__NODE__)
MOD:V-ADV (monocyte,to)
SUBJ:V_PASS-N (activate,activation)
SUBJ:V-N (macrophage,activation)

Analyse 17

      +-----------------------------------------SUBJ:V-N----------------------------------------+       
      +------------------------------------OBJ:V-N-----------------------------------+          |       
      |                   +-------------------------SUBJ:V-N-------------------------+          |       
      |                   +-----OBJ:V-N----+-------------MOD:V-ADV-------------+     |          |       
      +COMP:N-N(of+       |       +SUBJ:V-N+---OBJ:V-N--+--COMP:N-N(of)-+      |     |          |       
      |           |       |       |        |            |               |      |     |          |       
 Activation of __SP__ __NODE__ protein decreases differentiation of monocytes to activated macrophages .
COMP:N-N(of) (activation,__SP__)
OBJ:V-N (decrease,__NODE__)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,differentiation)
MOD:V-ADV (decrease,to)
COMP:N-N(of) (differentiation,monocyte)
OBJ:V-N (activate,activation)
SUBJ:V-N (activate,__NODE__)
SUBJ:V-N (macrophage,activation)

Analyse 18

      +-----------------------------------------SUBJ:V-N----------------------------------------+       
      |                   +-----------------------SUBJ:V_PASS-N----------------------+          |       
      +----COMP:N-N(of)---+-----OBJ:V-N----+-------------MOD:V-ADV-------------+     |          |       
      |           +MOD_ATT+       +SUBJ:V-N+---OBJ:V-N--+--COMP:N-N(of)-+      |     |          |       
      |           |       |       |        |            |               |      |     |          |       
 Activation of __SP__ __NODE__ protein decreases differentiation of monocytes to activated macrophages .
COMP:N-N(of) (activation,__NODE__)
MOD_ATT:N-ADJ (__NODE__,__SP__)
OBJ:V-N (decrease,__NODE__)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,differentiation)
MOD:V-ADV (decrease,to)
COMP:N-N(of) (differentiation,monocyte)
SUBJ:V_PASS-N (activate,__NODE__)
SUBJ:V-N (macrophage,activation)

Analyse 19

      +-----------------------------------------SUBJ:V-N----------------------------------------+       
      |           +---------------------------SUBJ:V_PASS-N--------------------------+          |       
      |           +---------OBJ:V-N--------+-------------MOD:V-ADV-------------+     |          |       
      +COMP:N-N(of+       +MOD_ATT+SUBJ:V-N+---OBJ:V-N--+--COMP:N-N(of)-+      |     |          |       
      |           |       |       |        |            |               |      |     |          |       
 Activation of __SP__ __NODE__ protein decreases differentiation of monocytes to activated macrophages .
COMP:N-N(of) (activation,__SP__)
MOD_ATT:N-ADJ (protein,__NODE__)
OBJ:V-N (decrease,__SP__)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,differentiation)
MOD:V-ADV (decrease,to)
COMP:N-N(of) (differentiation,monocyte)
SUBJ:V_PASS-N (activate,__SP__)
SUBJ:V-N (macrophage,activation)

Analyse 20

      +-----------------------------------------SUBJ:V-N----------------------------------------+       
      +---------------------------------SUBJ:V_PASS-N--------------------------------+          |       
      +---------------OBJ:V-N--------------+-------------MOD:V-ADV-------------+     |          |       
      +COMP:N-N(of+       +MOD_ATT+SUBJ:V-N+---OBJ:V-N--+--COMP:N-N(of)-+      |     |          |       
      |           |       |       |        |            |               |      |     |          |       
 Activation of __SP__ __NODE__ protein decreases differentiation of monocytes to activated macrophages .
COMP:N-N(of) (activation,__SP__)
MOD_ATT:N-ADJ (protein,__NODE__)
OBJ:V-N (decrease,activation)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,differentiation)
MOD:V-ADV (decrease,to)
COMP:N-N(of) (differentiation,monocyte)
SUBJ:V_PASS-N (activate,activation)
SUBJ:V-N (macrophage,activation)

Analyse 21

      +-----------------------------------------SUBJ:V-N----------------------------------------+       
      +---------------------------------SUBJ:V_PASS-N--------------------------------+          |       
      +---------------OBJ:V-N--------------+                                         |          |       
      +----COMP:N-N(of)---+                +-------------MOD:V-ADV-------------+     |          |       
      |           +MOD_ATT+       +SUBJ:V-N+---OBJ:V-N--+--COMP:N-N(of)-+      |     |          |       
      |           |       |       |        |            |               |      |     |          |       
 Activation of __SP__ __NODE__ protein decreases differentiation of monocytes to activated macrophages .
COMP:N-N(of) (activation,__NODE__)
MOD_ATT:N-ADJ (__NODE__,__SP__)
OBJ:V-N (decrease,activation)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,differentiation)
MOD:V-ADV (decrease,to)
COMP:N-N(of) (differentiation,monocyte)
SUBJ:V_PASS-N (activate,activation)
SUBJ:V-N (macrophage,activation)

Analyse 22

      +-----------------------------------------SUBJ:V-N----------------------------------------+       
      |           +---------------------------SUBJ:V_PASS-N--------------------------+          |       
      |           +-----------------------OBJ:V-N-----------------------+            |          |       
      |           |       +-------------------SUBJ:V-N------------------+            |          |       
      |           |       +-----OBJ:V-N----+                            |            |          |       
      +COMP:N-N(of+       |       +SUBJ:V-N+---OBJ:V-N--+MOD_POST:+     +MOD:V-+     |          |       
      |           |       |       |        |            |         |     |      |     |          |       
 Activation of __SP__ __NODE__ protein decreases differentiation of monocytes to activated macrophages .
COMP:N-N(of) (activation,__SP__)
OBJ:V-N (decrease,__NODE__)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,differentiation)
MOD_POST:N-ADJ (differentiation,of)
OBJ:V-N (monocyte,__SP__)
SUBJ:V-N (monocyte,__NODE__)
MOD:V-ADV (monocyte,to)
SUBJ:V_PASS-N (activate,__SP__)
SUBJ:V-N (macrophage,activation)

Analyse 23

      +-----------------------------------------SUBJ:V-N----------------------------------------+       
      +---------------------------------SUBJ:V_PASS-N--------------------------------+          |       
      +-----------------------------OBJ:V-N-----------------------------+            |          |       
      |                   +-------------------SUBJ:V-N------------------+            |          |       
      |                   +-----OBJ:V-N----+                            |            |          |       
      +COMP:N-N(of+       |       +SUBJ:V-N+---OBJ:V-N--+MOD_POST:+     +MOD:V-+     |          |       
      |           |       |       |        |            |         |     |      |     |          |       
 Activation of __SP__ __NODE__ protein decreases differentiation of monocytes to activated macrophages .
COMP:N-N(of) (activation,__SP__)
OBJ:V-N (decrease,__NODE__)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,differentiation)
MOD_POST:N-ADJ (differentiation,of)
OBJ:V-N (monocyte,activation)
SUBJ:V-N (monocyte,__NODE__)
MOD:V-ADV (monocyte,to)
SUBJ:V_PASS-N (activate,activation)
SUBJ:V-N (macrophage,activation)