A protein chimera composed of a protein fragment from __SP__ __NODE__ protein and of a protein fragment containing a Fc domain from __SP__ __NODE__ in cell culture and a protein chimera composed of a protein fragment containing a Fc domain from __SP__ __NODE__ and of a protein fragment from __SP__ __NODE__ protein in cell culture and a protein chimera composed of a protein fragment containing a Fc domain from __SP__ __NODE__ and of a protein fragment from __SP__ __NODE__ protein in cell culture cause little or no change in death of HT290.14s cells treated with __NODE__ protein and with mutant __NODE__ protein ( N terminal truncation 1 65 with its cytoplasmic domain and its transmembrane domain deleted ) .