Validation pour Ingenuity205

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Ingenuity205

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Phrase 49 - PMID ?

In cell surface from HepG2 cells , a protein protein complex consisting of cleaved NODE containing a pro domain and of mutant cleaved gain of function NODE ( D374Y ) containing a catalytic domain increases degradation of SP NODE protein .

Non annotée
Je ne sais pas
Je n'ai pas trouvé d'analyse satisfaisante

Commentaires :

Analyse 0

                              +-----------------------------------------------------------------------------------COMP:V-N(In)-----------------------------------------------------------------------------------+                                             
                              |                                                                                  +-----------------COMP:N-N(of)-----------------+                                                |                                             
      +------MOD_ATT:N-N------+-----------APPOS----------+                                        +------------------OBJ:V-N-----------------+                  |                   +----------SUBJ:V-N----------+          +--------COMP:N-N(of)--------+     
      |     +---MOD_ATT:N-N---+          +--MOD_ATT:N-N--+         +----COMP:N-N(of)----+         +----OBJ:V-N---+             +MOD_ATT:N-ADJ+---COMP:N-N(of)---+                   +-------OBJ:V-N------+       |          |            +-MOD_ATT:N-ADJ-+     
      |     |           +MOD_A+          |       +MOD_ATT+-SUBJ:V-N+           +MOD_ATT:+-SUBJ:V-N+        +MOD_A+             |      +MOD_AT+         +MOD_ATT:+--APPOS-+          |           +MOD_ATT:+       +--OBJ:V-N-+            |       +MOD_ATT+     
      |     |           |     |          |       |       |         |           |        |         |        |     |             |      |      |         |        |        |          |           |        |       |          |            |       |       |     
 In cell surface from HepG2 cells , a protein protein complex consisting of cleaved __NODE__ containing a pro domain and of mutant cleaved gain of function __NODE__ ( D374Y ) containing a catalytic domain increases degradation of __SP__ __NODE__ protein .
MOD_ATT:N-N (cell,cell)
MOD_ATT:N-N (cell,surface)
MOD_ATT:N-N (cell,HepG2)
APPOS (cell,complex)
MOD_ATT:N-N (complex,protein)
MOD_ATT:N-N (complex,protein)
SUBJ:V-N (consist,complex)
COMP:N-N(of) (consist,__NODE__)
MOD_ATT:N-ADJ (__NODE__,cleave)
SUBJ:V-N (contain,__NODE__)
OBJ:V-N (contain,domain)
OBJ:V-N (contain,gain)
MOD_ATT:N-N (domain,pro)
COMP:N-N(of) (domain,__NODE__)
MOD_ATT:N-ADJ (gain,mutant)
MOD_ATT:N-ADJ (gain,cleave)
COMP:N-N(of) (gain,__NODE__)
MOD_ATT:N-N (__NODE__,function)
APPOS (__NODE__,D374Y)
OBJ:V-N (contain,domain)
MOD_ATT:N-ADJ (domain,catalytic)
COMP:V-N(In) (increase,cell)
SUBJ:V-N (increase,contain)
OBJ:V-N (increase,degradation)
COMP:N-N(of) (degradation,protein)
MOD_ATT:N-ADJ (protein,__SP__)
MOD_ATT:N-ADJ (protein,__NODE__)

Analyse 1

                              +-----------------------------------------------------------------------------------COMP:V-N(In)-----------------------------------------------------------------------------------+                                             
                              |                                                                                  +-----------------COMP:N-N(of)-----------------+                                                |                                             
      +------MOD_ATT:N-N------+-----------APPOS----------+----------------SUBJ:V-N----------------+------------------OBJ:V-N-----------------+                  |                   +----------SUBJ:V-N----------+          +--------COMP:N-N(of)--------+     
      |     +---MOD_ATT:N-N---+          +--MOD_ATT:N-N--+         +----COMP:N-N(of)----+         +----OBJ:V-N---+             +MOD_ATT:N-ADJ+---COMP:N-N(of)---+                   +-------OBJ:V-N------+       |          |            +-MOD_ATT:N-ADJ-+     
      |     |           +MOD_A+          |       +MOD_ATT+-SUBJ:V-N+           +MOD_ATT:+         |        +MOD_A+             |      +MOD_AT+         +MOD_ATT:+--APPOS-+          |           +MOD_ATT:+       +--OBJ:V-N-+            |       +MOD_ATT+     
      |     |           |     |          |       |       |         |           |        |         |        |     |             |      |      |         |        |        |          |           |        |       |          |            |       |       |     
 In cell surface from HepG2 cells , a protein protein complex consisting of cleaved __NODE__ containing a pro domain and of mutant cleaved gain of function __NODE__ ( D374Y ) containing a catalytic domain increases degradation of __SP__ __NODE__ protein .
MOD_ATT:N-N (cell,cell)
MOD_ATT:N-N (cell,surface)
MOD_ATT:N-N (cell,HepG2)
APPOS (cell,complex)
MOD_ATT:N-N (complex,protein)
MOD_ATT:N-N (complex,protein)
SUBJ:V-N (consist,complex)
COMP:N-N(of) (consist,__NODE__)
MOD_ATT:N-ADJ (__NODE__,cleave)
SUBJ:V-N (contain,complex)
OBJ:V-N (contain,domain)
OBJ:V-N (contain,gain)
MOD_ATT:N-N (domain,pro)
COMP:N-N(of) (domain,__NODE__)
MOD_ATT:N-ADJ (gain,mutant)
MOD_ATT:N-ADJ (gain,cleave)
COMP:N-N(of) (gain,__NODE__)
MOD_ATT:N-N (__NODE__,function)
APPOS (__NODE__,D374Y)
OBJ:V-N (contain,domain)
MOD_ATT:N-ADJ (domain,catalytic)
COMP:V-N(In) (increase,cell)
SUBJ:V-N (increase,contain)
OBJ:V-N (increase,degradation)
COMP:N-N(of) (degradation,protein)
MOD_ATT:N-ADJ (protein,__SP__)
MOD_ATT:N-ADJ (protein,__NODE__)

Analyse 2

                              +-----------------------------------------------------------------------------------COMP:V-N(In)-----------------------------------------------------------------------------------+                                             
                              |                                                         +------------------------------COMP:N-N(of)-----------------------------+                                                |                                             
      +------MOD_ATT:N-N------+-----------APPOS----------+                              |         +------------------OBJ:V-N-----------------+                  |                   +----------SUBJ:V-N----------+          +--------COMP:N-N(of)--------+     
      |     +---MOD_ATT:N-N---+          +--MOD_ATT:N-N--+         +----COMP:N-N(of)----+         +----OBJ:V-N---+             +MOD_ATT:N-ADJ+                  |                   +-------OBJ:V-N------+       |          |            +-MOD_ATT:N-ADJ-+     
      |     |           +MOD_A+          |       +MOD_ATT+-SUBJ:V-N+           +MOD_ATT:+-SUBJ:V-N+        +MOD_A+             |      +MOD_AT+         +MOD_ATT:+--APPOS-+          |           +MOD_ATT:+       +--OBJ:V-N-+            |       +MOD_ATT+     
      |     |           |     |          |       |       |         |           |        |         |        |     |             |      |      |         |        |        |          |           |        |       |          |            |       |       |     
 In cell surface from HepG2 cells , a protein protein complex consisting of cleaved __NODE__ containing a pro domain and of mutant cleaved gain of function __NODE__ ( D374Y ) containing a catalytic domain increases degradation of __SP__ __NODE__ protein .
MOD_ATT:N-N (cell,cell)
MOD_ATT:N-N (cell,surface)
MOD_ATT:N-N (cell,HepG2)
APPOS (cell,complex)
MOD_ATT:N-N (complex,protein)
MOD_ATT:N-N (complex,protein)
SUBJ:V-N (consist,complex)
COMP:N-N(of) (consist,__NODE__)
MOD_ATT:N-ADJ (__NODE__,cleave)
COMP:N-N(of) (__NODE__,__NODE__)
SUBJ:V-N (contain,__NODE__)
OBJ:V-N (contain,domain)
OBJ:V-N (contain,gain)
MOD_ATT:N-N (domain,pro)
MOD_ATT:N-ADJ (gain,mutant)
MOD_ATT:N-ADJ (gain,cleave)
MOD_ATT:N-N (__NODE__,function)
APPOS (__NODE__,D374Y)
OBJ:V-N (contain,domain)
MOD_ATT:N-ADJ (domain,catalytic)
COMP:V-N(In) (increase,cell)
SUBJ:V-N (increase,contain)
OBJ:V-N (increase,degradation)
COMP:N-N(of) (degradation,protein)
MOD_ATT:N-ADJ (protein,__SP__)
MOD_ATT:N-ADJ (protein,__NODE__)

Analyse 3

                              +-----------------------------------------------------------------------------------COMP:V-N(In)-----------------------------------------------------------------------------------+                                             
                              |                                                                                  +-----------------COMP:N-N(of)-----------------+                                                |                                             
      +------MOD_ATT:N-N------+-----------APPOS----------+                                        +------------------OBJ:V-N-----------------+                  |                   +----------SUBJ:V-N----------+          +--------COMP:N-N(of)--------+     
      |     +---MOD_ATT:N-N---+          +--MOD_ATT:N-N--+         +----COMP:N-N(of)----+         +----OBJ:V-N---+             +MOD_ATT:N-ADJ+---COMP:N-N(of)---+                   +-------OBJ:V-N------+       |          |            +-MOD_ATT:N-ADJ-+     
      |     |           +MOD_A+          |       +MOD_ATT+-SUBJ:V-N+           +MOD_ATT:+-SUBJ:V-N+        +MOD_A+             |      +MOD_AT+         +MOD_ATT:+--APPOS-+          |           +MOD_ATT:+       +--OBJ:V-N-+            |       +MOD_ATT+     
      |     |           |     |          |       |       |         |           |        |         |        |     |             |      |      |         |        |        |          |           |        |       |          |            |       |       |     
 In cell surface from HepG2 cells , a protein protein complex consisting of cleaved __NODE__ containing a pro domain and of mutant cleaved gain of function __NODE__ ( D374Y ) containing a catalytic domain increases degradation of __SP__ __NODE__ protein .
MOD_ATT:N-N (cell,cell)
MOD_ATT:N-N (cell,surface)
MOD_ATT:N-N (cell,HepG2)
APPOS (cell,complex)
MOD_ATT:N-N (complex,protein)
MOD_ATT:N-N (complex,protein)
SUBJ:V-N (consist,complex)
COMP:N-N(of) (consist,__NODE__)
MOD_ATT:N-ADJ (__NODE__,cleave)
SUBJ:V-N (contain,__NODE__)
OBJ:V-N (contain,domain)
OBJ:V-N (contain,gain)
MOD_ATT:N-N (domain,pro)
COMP:N-N(of) (domain,__NODE__)
MOD_ATT:N-ADJ (gain,mutant)
MOD_ATT:N-ADJ (gain,cleave)
COMP:N-N(of) (gain,__NODE__)
MOD_ATT:N-N (__NODE__,function)
APPOS (__NODE__,D374Y)
OBJ:V-N (contain,domain)
MOD_ATT:N-ADJ (domain,catalytic)
COMP:V-N(In) (increase,cell)
SUBJ:V-N (increase,contain)
OBJ:V-N (increase,degradation)
COMP:N-N(of) (degradation,protein)
MOD_ATT:N-ADJ (protein,__SP__)
MOD_ATT:N-ADJ (protein,__NODE__)

Analyse 4

                              +-----------------------------------------------------------------------------------COMP:V-N(In)-----------------------------------------------------------------------------------+                                             
                              |                                                                                  +-----------------COMP:N-N(of)-----------------+                                                |                                             
      +------MOD_ATT:N-N------+-----------APPOS----------+----------------SUBJ:V-N----------------+------------------OBJ:V-N-----------------+                  |                   +----------SUBJ:V-N----------+          +--------COMP:N-N(of)--------+     
      |     +---MOD_ATT:N-N---+          +--MOD_ATT:N-N--+         +----COMP:N-N(of)----+         +----OBJ:V-N---+             +MOD_ATT:N-ADJ+---COMP:N-N(of)---+                   +-------OBJ:V-N------+       |          |            +-MOD_ATT:N-ADJ-+     
      |     |           +MOD_A+          |       +MOD_ATT+-SUBJ:V-N+           +MOD_ATT:+         |        +MOD_A+             |      +MOD_AT+         +MOD_ATT:+--APPOS-+          |           +MOD_ATT:+       +--OBJ:V-N-+            |       +MOD_ATT+     
      |     |           |     |          |       |       |         |           |        |         |        |     |             |      |      |         |        |        |          |           |        |       |          |            |       |       |     
 In cell surface from HepG2 cells , a protein protein complex consisting of cleaved __NODE__ containing a pro domain and of mutant cleaved gain of function __NODE__ ( D374Y ) containing a catalytic domain increases degradation of __SP__ __NODE__ protein .
MOD_ATT:N-N (cell,cell)
MOD_ATT:N-N (cell,surface)
MOD_ATT:N-N (cell,HepG2)
APPOS (cell,complex)
MOD_ATT:N-N (complex,protein)
MOD_ATT:N-N (complex,protein)
SUBJ:V-N (consist,complex)
COMP:N-N(of) (consist,__NODE__)
MOD_ATT:N-ADJ (__NODE__,cleave)
SUBJ:V-N (contain,complex)
OBJ:V-N (contain,domain)
OBJ:V-N (contain,gain)
MOD_ATT:N-N (domain,pro)
COMP:N-N(of) (domain,__NODE__)
MOD_ATT:N-ADJ (gain,mutant)
MOD_ATT:N-ADJ (gain,cleave)
COMP:N-N(of) (gain,__NODE__)
MOD_ATT:N-N (__NODE__,function)
APPOS (__NODE__,D374Y)
OBJ:V-N (contain,domain)
MOD_ATT:N-ADJ (domain,catalytic)
COMP:V-N(In) (increase,cell)
SUBJ:V-N (increase,contain)
OBJ:V-N (increase,degradation)
COMP:N-N(of) (degradation,protein)
MOD_ATT:N-ADJ (protein,__SP__)
MOD_ATT:N-ADJ (protein,__NODE__)

Analyse 5

                              +-----------------------------------------------------------------------------------COMP:V-N(In)-----------------------------------------------------------------------------------+                                             
                              |                                                         +------------------------------COMP:N-N(of)-----------------------------+                                                |                                             
      +------MOD_ATT:N-N------+-----------APPOS----------+                              |         +------------------OBJ:V-N-----------------+                  |                   +----------SUBJ:V-N----------+          +--------COMP:N-N(of)--------+     
      |     +---MOD_ATT:N-N---+          +--MOD_ATT:N-N--+         +----COMP:N-N(of)----+         +----OBJ:V-N---+             +MOD_ATT:N-ADJ+                  |                   +-------OBJ:V-N------+       |          |            +-MOD_ATT:N-ADJ-+     
      |     |           +MOD_A+          |       +MOD_ATT+-SUBJ:V-N+           +MOD_ATT:+-SUBJ:V-N+        +MOD_A+             |      +MOD_AT+         +MOD_ATT:+--APPOS-+          |           +MOD_ATT:+       +--OBJ:V-N-+            |       +MOD_ATT+     
      |     |           |     |          |       |       |         |           |        |         |        |     |             |      |      |         |        |        |          |           |        |       |          |            |       |       |     
 In cell surface from HepG2 cells , a protein protein complex consisting of cleaved __NODE__ containing a pro domain and of mutant cleaved gain of function __NODE__ ( D374Y ) containing a catalytic domain increases degradation of __SP__ __NODE__ protein .
MOD_ATT:N-N (cell,cell)
MOD_ATT:N-N (cell,surface)
MOD_ATT:N-N (cell,HepG2)
APPOS (cell,complex)
MOD_ATT:N-N (complex,protein)
MOD_ATT:N-N (complex,protein)
SUBJ:V-N (consist,complex)
COMP:N-N(of) (consist,__NODE__)
MOD_ATT:N-ADJ (__NODE__,cleave)
COMP:N-N(of) (__NODE__,__NODE__)
SUBJ:V-N (contain,__NODE__)
OBJ:V-N (contain,domain)
OBJ:V-N (contain,gain)
MOD_ATT:N-N (domain,pro)
MOD_ATT:N-ADJ (gain,mutant)
MOD_ATT:N-ADJ (gain,cleave)
MOD_ATT:N-N (__NODE__,function)
APPOS (__NODE__,D374Y)
OBJ:V-N (contain,domain)
MOD_ATT:N-ADJ (domain,catalytic)
COMP:V-N(In) (increase,cell)
SUBJ:V-N (increase,contain)
OBJ:V-N (increase,degradation)
COMP:N-N(of) (degradation,protein)
MOD_ATT:N-ADJ (protein,__SP__)
MOD_ATT:N-ADJ (protein,__NODE__)

Analyse 6

                              +-----------------------------------------------------------------------------------COMP:V-N(In)-----------------------------------------------------------------------------------+                                             
                              |                          +------------------------------------------------------------------------SUBJ:V-N-----------------------------------------------------------------------+                                             
      +------MOD_ATT:N-N------+------------COMP:V-N(In)------------+                              +------------------OBJ:V-N-----------------+---------------SUBJ:V-N---------------+                            |          +--------COMP:N-N(of)--------+     
      |     +---MOD_ATT:N-N---+          +--MOD_ATT:N-N--+         +----COMP:N-N(of)----+         +----OBJ:V-N---+             +MOD_ATT:N-ADJ+---COMP:N-N(of)---+                   +-------OBJ:V-N------+       |          |            +-MOD_ATT:N-ADJ-+     
      |     |           +MOD_A+          |       +MOD_ATT+-SUBJ:V-N+           +MOD_ATT:+-SUBJ:V-N+        +MOD_A+             |      +MOD_AT+         +MOD_ATT:+--APPOS-+          |           +MOD_ATT:+       +--OBJ:V-N-+            |       +MOD_ATT+     
      |     |           |     |          |       |       |         |           |        |         |        |     |             |      |      |         |        |        |          |           |        |       |          |            |       |       |     
 In cell surface from HepG2 cells , a protein protein complex consisting of cleaved __NODE__ containing a pro domain and of mutant cleaved gain of function __NODE__ ( D374Y ) containing a catalytic domain increases degradation of __SP__ __NODE__ protein .
MOD_ATT:N-N (cell,cell)
MOD_ATT:N-N (cell,surface)
MOD_ATT:N-N (cell,HepG2)
MOD_ATT:N-N (complex,protein)
MOD_ATT:N-N (complex,protein)
COMP:V-N(In) (consist,cell)
SUBJ:V-N (consist,complex)
COMP:N-N(of) (consist,__NODE__)
MOD_ATT:N-ADJ (__NODE__,cleave)
SUBJ:V-N (contain,__NODE__)
OBJ:V-N (contain,domain)
OBJ:V-N (contain,gain)
MOD_ATT:N-N (domain,pro)
MOD_ATT:N-ADJ (gain,mutant)
MOD_ATT:N-ADJ (gain,cleave)
COMP:N-N(of) (gain,__NODE__)
MOD_ATT:N-N (__NODE__,function)
APPOS (__NODE__,D374Y)
SUBJ:V-N (contain,gain)
OBJ:V-N (contain,domain)
MOD_ATT:N-ADJ (domain,catalytic)
COMP:V-N(In) (increase,cell)
SUBJ:V-N (increase,complex)
OBJ:V-N (increase,degradation)
COMP:N-N(of) (degradation,protein)
MOD_ATT:N-ADJ (protein,__SP__)
MOD_ATT:N-ADJ (protein,__NODE__)

Analyse 7

                              +-----------------------------------------------------------------------------------COMP:V-N(In)-----------------------------------------------------------------------------------+                                             
                              |                          +------------------------------------------------------------------------SUBJ:V-N-----------------------------------------------------------------------+                                             
                              +----------------------------COMP:V-N(In)---------------------------+                                                                                                              |                                             
                              |                          +----------------SUBJ:V-N----------------+                                                                                                              |                                             
      +------MOD_ATT:N-N------+------------COMP:V-N(In)------------+                              +------------------OBJ:V-N-----------------+---------------SUBJ:V-N---------------+                            |          +--------COMP:N-N(of)--------+     
      |     +---MOD_ATT:N-N---+          +--MOD_ATT:N-N--+         +----COMP:N-N(of)----+         +----OBJ:V-N---+             +MOD_ATT:N-ADJ+---COMP:N-N(of)---+                   +-------OBJ:V-N------+       |          |            +-MOD_ATT:N-ADJ-+     
      |     |           +MOD_A+          |       +MOD_ATT+-SUBJ:V-N+           +MOD_ATT:+         |        +MOD_A+             |      +MOD_AT+         +MOD_ATT:+--APPOS-+          |           +MOD_ATT:+       +--OBJ:V-N-+            |       +MOD_ATT+     
      |     |           |     |          |       |       |         |           |        |         |        |     |             |      |      |         |        |        |          |           |        |       |          |            |       |       |     
 In cell surface from HepG2 cells , a protein protein complex consisting of cleaved __NODE__ containing a pro domain and of mutant cleaved gain of function __NODE__ ( D374Y ) containing a catalytic domain increases degradation of __SP__ __NODE__ protein .
MOD_ATT:N-N (cell,cell)
MOD_ATT:N-N (cell,surface)
MOD_ATT:N-N (cell,HepG2)
MOD_ATT:N-N (complex,protein)
MOD_ATT:N-N (complex,protein)
COMP:V-N(In) (consist,cell)
SUBJ:V-N (consist,complex)
COMP:N-N(of) (consist,__NODE__)
MOD_ATT:N-ADJ (__NODE__,cleave)
COMP:V-N(In) (contain,cell)
SUBJ:V-N (contain,complex)
OBJ:V-N (contain,domain)
OBJ:V-N (contain,gain)
MOD_ATT:N-N (domain,pro)
MOD_ATT:N-ADJ (gain,mutant)
MOD_ATT:N-ADJ (gain,cleave)
COMP:N-N(of) (gain,__NODE__)
MOD_ATT:N-N (__NODE__,function)
APPOS (__NODE__,D374Y)
SUBJ:V-N (contain,gain)
OBJ:V-N (contain,domain)
MOD_ATT:N-ADJ (domain,catalytic)
COMP:V-N(In) (increase,cell)
SUBJ:V-N (increase,complex)
OBJ:V-N (increase,degradation)
COMP:N-N(of) (degradation,protein)
MOD_ATT:N-ADJ (protein,__SP__)
MOD_ATT:N-ADJ (protein,__NODE__)