Validation pour Ingenuity221

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Ingenuity221

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Phrase 54 - PMID ?

In differentiating 3T3 L1 cells , dominant negative mutant ADD 1 [NODE] protein ( Y320A with its DNA binding domain mutated C terminal truncation 404 End ) decreases expression of SP Cbf a [NODE] mRNA .

Non annotée
Je ne sais pas
Je n'ai pas trouvé d'analyse satisfaisante

Commentaires :

Analyse 0

  +-----------------------------------------------------------------------------MOD:V-ADV----------------------------------------------------------------------------+                                                 
  |                                                                             +--------------------------------------SUBJ:V-N--------------------------------------+                                                 
  |                                                                             |              +---------------------------OBJ:V-N--------------------------+        |                                                 
  |                                                                             |              |       +---------------MOD_ATT:N-N---------------+          |        |                                                 
  |                                    +--------------MOD_ATT:N-ADJ-------------+              |       |     +------------MOD_ATT:N-N------------+          |        |                                                 
  |                                    |        +---------MOD_ATT:N-ADJ---------+              |       |     |       +--------MOD_ATT:N-N--------+          |        |          +-----------COMP:N-N(of)-----------+   
  |        +-----OBJ:V-N-----+         |        |       +-----MOD_ATT:N-ADJ-----+              |       |     |       |      +----MOD_ATT:N-ADJ---+          |        |          |           +-----MOD_ATT:N-ADJ----+   
  |        |         +MOD_ATT+         |        |       |       +--MOD_ATT:N-N--+              |       |     |       |      |    +--MOD_ATT:N-N--+          |        |          |           |    +---MOD_ATT:N-N---+   
  |        |         |   +MOD+         |        |       |       |      +MOD_ATT:+              |       |     |       |      |    |     +MOD_ATT:N+      +MOD+        +--OBJ:V-N-+           |    |         +MOD_ATT+   
  |        |         |   |   |         |        |       |       |      |        |              |       |     |       |      |    |     |         |      |   |        |          |           |    |         |       |   
 In differentiating 3T3 L1 cells , dominant negative mutant ADD 1 [__NODE__] protein ( Y320A with its DNA binding domain mutated C terminal truncation 404 End ) decreases expression of __SP__ Cbf a [__NODE__] mRNA .
OBJ:V-N (differentiate,cell)
MOD_ATT:N-ADJ (cell,3T3)
MOD_ATT:N-N (cell,L1)
MOD_ATT:N-ADJ (protein,dominant)
MOD_ATT:N-ADJ (protein,negative)
MOD_ATT:N-ADJ (protein,mutant)
MOD_ATT:N-N (protein,1)
MOD_ATT:N-N (protein,[__NODE__])
OBJ:V-N (with,end)
MOD_ATT:N-N (truncation,DNA)
MOD_ATT:N-N (truncation,bind)
MOD_ATT:N-N (truncation,domain)
MOD_ATT:N-ADJ (truncation,mutate)
MOD_ATT:N-N (truncation,C)
MOD_ATT:N-N (truncation,terminal)
MOD_ATT:N-ADJ (end,@card@)
MOD:V-ADV (decrease,in)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,expression)
COMP:N-N(of) (expression,mRNA)
MOD_ATT:N-ADJ (mRNA,__SP__)
MOD_ATT:N-N (mRNA,Cbf)
MOD_ATT:N-N (mRNA,[__NODE__])

Analyse 1

                             +--------------------------------------------------------------COMP:V-N(In)-------------------------------------------------------------+                                                 
                             |                                                  +--------------------------------------SUBJ:V-N--------------------------------------+                                                 
                             |                                                  |              +---------------------------OBJ:V-N--------------------------+        |                                                 
                             |                                                  |              |       +---------------MOD_ATT:N-N---------------+          |        |                                                 
                             |         +--------------MOD_ATT:N-ADJ-------------+              |       |     +------------MOD_ATT:N-N------------+          |        |                                                 
                             |         |        +---------MOD_ATT:N-ADJ---------+              |       |     |       +--------MOD_ATT:N-N--------+          |        |          +-----------COMP:N-N(of)-----------+   
           +--MOD_ATT:N-ADJ--+         |        |       +-----MOD_ATT:N-ADJ-----+              |       |     |       |      +----MOD_ATT:N-ADJ---+          |        |          |           +-----MOD_ATT:N-ADJ----+   
           |         +MOD_ATT+         |        |       |       +--MOD_ATT:N-N--+              |       |     |       |      |    +--MOD_ATT:N-N--+          |        |          |           |    +---MOD_ATT:N-N---+   
           |         |   +MOD+         |        |       |       |      +MOD_ATT:+              |       |     |       |      |    |     +MOD_ATT:N+      +MOD+        +--OBJ:V-N-+           |    |         +MOD_ATT+   
           |         |   |   |         |        |       |       |      |        |              |       |     |       |      |    |     |         |      |   |        |          |           |    |         |       |   
 In differentiating 3T3 L1 cells , dominant negative mutant ADD 1 [__NODE__] protein ( Y320A with its DNA binding domain mutated C terminal truncation 404 End ) decreases expression of __SP__ Cbf a [__NODE__] mRNA .
MOD_ATT:N-ADJ (cell,differentiate)
MOD_ATT:N-ADJ (cell,3T3)
MOD_ATT:N-N (cell,L1)
MOD_ATT:N-ADJ (protein,dominant)
MOD_ATT:N-ADJ (protein,negative)
MOD_ATT:N-ADJ (protein,mutant)
MOD_ATT:N-N (protein,1)
MOD_ATT:N-N (protein,[__NODE__])
OBJ:V-N (with,end)
MOD_ATT:N-N (truncation,DNA)
MOD_ATT:N-N (truncation,bind)
MOD_ATT:N-N (truncation,domain)
MOD_ATT:N-ADJ (truncation,mutate)
MOD_ATT:N-N (truncation,C)
MOD_ATT:N-N (truncation,terminal)
MOD_ATT:N-ADJ (end,@card@)
COMP:V-N(In) (decrease,cell)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,expression)
COMP:N-N(of) (expression,mRNA)
MOD_ATT:N-ADJ (mRNA,__SP__)
MOD_ATT:N-N (mRNA,Cbf)
MOD_ATT:N-N (mRNA,[__NODE__])

Analyse 2

                             +--------------------------------------------------------------COMP:V-N(In)-------------------------------------------------------------+                                                 
                             |                                                  +--------------------------------------SUBJ:V-N--------------------------------------+                                                 
                             |                                                  |              +---------------------------OBJ:V-N--------------------------+        |                                                 
                             |                                                  |              |       +---------------MOD_ATT:N-N---------------+          |        |                                                 
                             |         +--------------MOD_ATT:N-ADJ-------------+              |       |     +------------MOD_ATT:N-N------------+          |        |                                                 
                             |         |        +---------MOD_ATT:N-ADJ---------+              |       |     |       +--------MOD_ATT:N-N--------+          |        |          +-----------COMP:N-N(of)-----------+   
           +---MOD_ATT:N-N---+         |        |       +-----MOD_ATT:N-ADJ-----+              |       |     |       |      +----MOD_ATT:N-ADJ---+          |        |          |           +-----MOD_ATT:N-ADJ----+   
           |         +MOD_ATT+         |        |       |       +--MOD_ATT:N-N--+              |       |     |       |      |    +--MOD_ATT:N-N--+          |        |          |           |    +---MOD_ATT:N-N---+   
           |         |   +MOD+         |        |       |       |      +MOD_ATT:+              |       |     |       |      |    |     +MOD_ATT:N+      +MOD+        +--OBJ:V-N-+           |    |         +MOD_ATT+   
           |         |   |   |         |        |       |       |      |        |              |       |     |       |      |    |     |         |      |   |        |          |           |    |         |       |   
 In differentiating 3T3 L1 cells , dominant negative mutant ADD 1 [__NODE__] protein ( Y320A with its DNA binding domain mutated C terminal truncation 404 End ) decreases expression of __SP__ Cbf a [__NODE__] mRNA .
MOD_ATT:N-N (cell,differentiate)
MOD_ATT:N-ADJ (cell,3T3)
MOD_ATT:N-N (cell,L1)
MOD_ATT:N-ADJ (protein,dominant)
MOD_ATT:N-ADJ (protein,negative)
MOD_ATT:N-ADJ (protein,mutant)
MOD_ATT:N-N (protein,1)
MOD_ATT:N-N (protein,[__NODE__])
OBJ:V-N (with,end)
MOD_ATT:N-N (truncation,DNA)
MOD_ATT:N-N (truncation,bind)
MOD_ATT:N-N (truncation,domain)
MOD_ATT:N-ADJ (truncation,mutate)
MOD_ATT:N-N (truncation,C)
MOD_ATT:N-N (truncation,terminal)
MOD_ATT:N-ADJ (end,@card@)
COMP:V-N(In) (decrease,cell)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,expression)
COMP:N-N(of) (expression,mRNA)
MOD_ATT:N-ADJ (mRNA,__SP__)
MOD_ATT:N-N (mRNA,Cbf)
MOD_ATT:N-N (mRNA,[__NODE__])