In nih3t3 cell , binding of __NODE__ protein and a protein chimera composed of a protein fragment ( 686 887 ) from __SP__ __NODE__ protein and of a protein fragment ( 903 1100 ) from __SP__ __NODE__ protein and of a protein fragment ( WQQQSYLDSGIHSTDA ) from __NODE__ protein is greater than binding of __NODE__ protein and a protein fragment ( 686 1100 ) containing a __NODE__ phosphorylation site 1 6 from __SP__ __NODE__ protein .