+----------------COMP:V-N(In)---------------+                            
       |             +-----------SUBJ:V-N----------+                            
       |             +----COMP:N-N(of)----+        |                            
       |             |            +MOD_ATT+        +-OBJ:V-N-+COMP:N-N(of)+     
       |             |            |       |        |         |            |     
 In plasma , up regulation of __NODE__ protein increases clearance of __NODE__ .
COMP:N-N(of) (regulation,protein)
MOD_ATT:N-ADJ (protein,__NODE__)
COMP:V-N(In) (increase,plasma)
SUBJ:V-N (increase,regulation)
OBJ:V-N (increase,clearance)
COMP:N-N(of) (clearance,__NODE__)