Validation pour Ingenuity293

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Ingenuity293

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Phrase 36 - PMID ?

In primary SP adipocytes , mutant NODE protein ( H215R with its DNA binding domain mutated ) decreases transcription of DNA endogenous promoter from SP NODE gene .

Non annotée
Je ne sais pas
Je n'ai pas trouvé d'analyse satisfaisante

Commentaires :

Analyse 0

                        +-----------------------------------COMP:V-N(In)----------------------------------+                                                                         
                        |                          +-----------------------SUBJ:V-N-----------------------+                                                                         
       +--MOD_ATT:N-ADJ-+          +-MOD_ATT:N-ADJ-+                      +-MOD_ATT:N-N-+                 |           +---MOD_POST:N-ADJ--+-------COMP:ADJ-N(from)-------+          
       |       +MOD_ATT:+          |       +MOD_ATT+                      |     +MOD_ATT+SUBJ:V+          +--OBJ:V-N--+COMP:N-N(of+       |                      +MOD_ATT+          
       |       |        |          |       |       |                      |     |       |      |          |           |           |       |                      |       |          
 In primary __SP__ adipocytes , mutant __NODE__ protein ( H215R with its DNA binding domain mutated ) decreases transcription of DNA endogenous promoter from __SP__ __NODE__ gene .
MOD_ATT:N-ADJ (adipocytes,primary)
MOD_ATT:N-ADJ (adipocytes,__SP__)
MOD_ATT:N-ADJ (protein,mutant)
MOD_ATT:N-ADJ (protein,__NODE__)
MOD_ATT:N-N (domain,DNA)
MOD_ATT:N-ADJ (domain,bind)
SUBJ:V_PASS-N (mutate,domain)
COMP:V-N(In) (decrease,adipocytes)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,transcription)
COMP:N-N(of) (transcription,DNA)
MOD_POST:N-ADJ (transcription,endogenous)
COMP:ADJ-N(from) (endogenous,__NODE__)
MOD_ATT:N-ADJ (__NODE__,__SP__)

Analyse 1

                        +-----------------------------------COMP:V-N(In)----------------------------------+                                                                         
                        |                          +-----------------------SUBJ:V-N-----------------------+                                                                         
       +--MOD_ATT:N-ADJ-+          +-MOD_ATT:N-ADJ-+                      +-MOD_ATT:N-N-+                 |           +---MOD_POST:N-ADJ--+-------COMP:ADJ-N(from)-------+          
       |       +MOD_ATT:+          |       +MOD_ATT+                      |     +MOD_ATT+SUBJ:V+          +--OBJ:V-N--+COMP:N-N(of+       |                      +MOD_ATT+          
       |       |        |          |       |       |                      |     |       |      |          |           |           |       |                      |       |          
 In primary __SP__ adipocytes , mutant __NODE__ protein ( H215R with its DNA binding domain mutated ) decreases transcription of DNA endogenous promoter from __SP__ __NODE__ gene .
MOD_ATT:N-ADJ (adipocytes,primary)
MOD_ATT:N-ADJ (adipocytes,__SP__)
MOD_ATT:N-ADJ (protein,mutant)
MOD_ATT:N-ADJ (protein,__NODE__)
MOD_ATT:N-N (domain,DNA)
MOD_ATT:N-N (domain,bind)
SUBJ:V_PASS-N (mutate,domain)
COMP:V-N(In) (decrease,adipocytes)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,transcription)
COMP:N-N(of) (transcription,DNA)
MOD_POST:N-ADJ (transcription,endogenous)
COMP:ADJ-N(from) (endogenous,__NODE__)
MOD_ATT:N-ADJ (__NODE__,__SP__)

Analyse 2

                        +-----------------------------------COMP:V-N(In)----------------------------------+                                                                         
                        |                          +-----------------------SUBJ:V-N-----------------------+                                                                         
       +--MOD_ATT:N-ADJ-+          +-MOD_ATT:N-ADJ-+                      +-MOD_ATT:N-N-+                 |           +---MOD_POST:N-ADJ--+-------COMP:ADJ-N(from)-------+          
       |       +MOD_ATT:+          |       +MOD_ATT+                      |     +MOD_ATT+                 +--OBJ:V-N--+COMP:N-N(of+       |                      +MOD_ATT+          
       |       |        |          |       |       |                      |     |       |                 |           |           |       |                      |       |          
 In primary __SP__ adipocytes , mutant __NODE__ protein ( H215R with its DNA binding domain mutated ) decreases transcription of DNA endogenous promoter from __SP__ __NODE__ gene .
MOD_ATT:N-ADJ (adipocytes,primary)
MOD_ATT:N-ADJ (adipocytes,__SP__)
MOD_ATT:N-ADJ (protein,mutant)
MOD_ATT:N-ADJ (protein,__NODE__)
MOD_ATT:N-N (domain,DNA)
MOD_ATT:N-ADJ (domain,bind)
COMP:V-N(In) (decrease,adipocytes)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,transcription)
COMP:N-N(of) (transcription,DNA)
MOD_POST:N-ADJ (transcription,endogenous)
COMP:ADJ-N(from) (endogenous,__NODE__)
MOD_ATT:N-ADJ (__NODE__,__SP__)

Analyse 3

                        +-----------------------------------COMP:V-N(In)----------------------------------+                                                                         
                        |                          +-----------------------SUBJ:V-N-----------------------+                                                                         
       +--MOD_ATT:N-ADJ-+          +-MOD_ATT:N-ADJ-+                      +-MOD_ATT:N-N-+                 |           +---MOD_POST:N-ADJ--+-------COMP:ADJ-N(from)-------+          
       |       +MOD_ATT:+          |       +MOD_ATT+                      |     +MOD_ATT+                 +--OBJ:V-N--+COMP:N-N(of+       |                      +MOD_ATT+          
       |       |        |          |       |       |                      |     |       |                 |           |           |       |                      |       |          
 In primary __SP__ adipocytes , mutant __NODE__ protein ( H215R with its DNA binding domain mutated ) decreases transcription of DNA endogenous promoter from __SP__ __NODE__ gene .
MOD_ATT:N-ADJ (adipocytes,primary)
MOD_ATT:N-ADJ (adipocytes,__SP__)
MOD_ATT:N-ADJ (protein,mutant)
MOD_ATT:N-ADJ (protein,__NODE__)
MOD_ATT:N-N (domain,DNA)
MOD_ATT:N-N (domain,bind)
COMP:V-N(In) (decrease,adipocytes)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,transcription)
COMP:N-N(of) (transcription,DNA)
MOD_POST:N-ADJ (transcription,endogenous)
COMP:ADJ-N(from) (endogenous,__NODE__)
MOD_ATT:N-ADJ (__NODE__,__SP__)

Analyse 4

                        +-----------------------------------COMP:V-N(In)----------------------------------+                                                                         
                        |                          +-----------------------SUBJ:V-N-----------------------+                                                                         
       +---MOD_ATT:N-N--+          +-MOD_ATT:N-ADJ-+                      +-MOD_ATT:N-N-+                 |           +---MOD_POST:N-ADJ--+-------COMP:ADJ-N(from)-------+          
       |       +MOD_ATT:+          |       +MOD_ATT+                      |     +MOD_ATT+SUBJ:V+          +--OBJ:V-N--+COMP:N-N(of+       |                      +MOD_ATT+          
       |       |        |          |       |       |                      |     |       |      |          |           |           |       |                      |       |          
 In primary __SP__ adipocytes , mutant __NODE__ protein ( H215R with its DNA binding domain mutated ) decreases transcription of DNA endogenous promoter from __SP__ __NODE__ gene .
MOD_ATT:N-N (adipocytes,primary)
MOD_ATT:N-ADJ (adipocytes,__SP__)
MOD_ATT:N-ADJ (protein,mutant)
MOD_ATT:N-ADJ (protein,__NODE__)
MOD_ATT:N-N (domain,DNA)
MOD_ATT:N-ADJ (domain,bind)
SUBJ:V_PASS-N (mutate,domain)
COMP:V-N(In) (decrease,adipocytes)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,transcription)
COMP:N-N(of) (transcription,DNA)
MOD_POST:N-ADJ (transcription,endogenous)
COMP:ADJ-N(from) (endogenous,__NODE__)
MOD_ATT:N-ADJ (__NODE__,__SP__)

Analyse 5

                        +-----------------------------------COMP:V-N(In)----------------------------------+                                                                         
                        |                          +-----------------------SUBJ:V-N-----------------------+                                                                         
       +---MOD_ATT:N-N--+          +-MOD_ATT:N-ADJ-+                      +-MOD_ATT:N-N-+                 |           +---MOD_POST:N-ADJ--+-------COMP:ADJ-N(from)-------+          
       |       +MOD_ATT:+          |       +MOD_ATT+                      |     +MOD_ATT+SUBJ:V+          +--OBJ:V-N--+COMP:N-N(of+       |                      +MOD_ATT+          
       |       |        |          |       |       |                      |     |       |      |          |           |           |       |                      |       |          
 In primary __SP__ adipocytes , mutant __NODE__ protein ( H215R with its DNA binding domain mutated ) decreases transcription of DNA endogenous promoter from __SP__ __NODE__ gene .
MOD_ATT:N-N (adipocytes,primary)
MOD_ATT:N-ADJ (adipocytes,__SP__)
MOD_ATT:N-ADJ (protein,mutant)
MOD_ATT:N-ADJ (protein,__NODE__)
MOD_ATT:N-N (domain,DNA)
MOD_ATT:N-N (domain,bind)
SUBJ:V_PASS-N (mutate,domain)
COMP:V-N(In) (decrease,adipocytes)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,transcription)
COMP:N-N(of) (transcription,DNA)
MOD_POST:N-ADJ (transcription,endogenous)
COMP:ADJ-N(from) (endogenous,__NODE__)
MOD_ATT:N-ADJ (__NODE__,__SP__)

Analyse 6

                        +-----------------------------------COMP:V-N(In)----------------------------------+                                                                         
                        |                          +-----------------------SUBJ:V-N-----------------------+                                                                         
       +---MOD_ATT:N-N--+          +-MOD_ATT:N-ADJ-+                      +-MOD_ATT:N-N-+                 |           +---MOD_POST:N-ADJ--+-------COMP:ADJ-N(from)-------+          
       |       +MOD_ATT:+          |       +MOD_ATT+                      |     +MOD_ATT+                 +--OBJ:V-N--+COMP:N-N(of+       |                      +MOD_ATT+          
       |       |        |          |       |       |                      |     |       |                 |           |           |       |                      |       |          
 In primary __SP__ adipocytes , mutant __NODE__ protein ( H215R with its DNA binding domain mutated ) decreases transcription of DNA endogenous promoter from __SP__ __NODE__ gene .
MOD_ATT:N-N (adipocytes,primary)
MOD_ATT:N-ADJ (adipocytes,__SP__)
MOD_ATT:N-ADJ (protein,mutant)
MOD_ATT:N-ADJ (protein,__NODE__)
MOD_ATT:N-N (domain,DNA)
MOD_ATT:N-ADJ (domain,bind)
COMP:V-N(In) (decrease,adipocytes)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,transcription)
COMP:N-N(of) (transcription,DNA)
MOD_POST:N-ADJ (transcription,endogenous)
COMP:ADJ-N(from) (endogenous,__NODE__)
MOD_ATT:N-ADJ (__NODE__,__SP__)

Analyse 7

                        +-----------------------------------COMP:V-N(In)----------------------------------+                                                                         
                        |                          +-----------------------SUBJ:V-N-----------------------+                                                                         
       +---MOD_ATT:N-N--+          +-MOD_ATT:N-ADJ-+                      +-MOD_ATT:N-N-+                 |           +---MOD_POST:N-ADJ--+-------COMP:ADJ-N(from)-------+          
       |       +MOD_ATT:+          |       +MOD_ATT+                      |     +MOD_ATT+                 +--OBJ:V-N--+COMP:N-N(of+       |                      +MOD_ATT+          
       |       |        |          |       |       |                      |     |       |                 |           |           |       |                      |       |          
 In primary __SP__ adipocytes , mutant __NODE__ protein ( H215R with its DNA binding domain mutated ) decreases transcription of DNA endogenous promoter from __SP__ __NODE__ gene .
MOD_ATT:N-N (adipocytes,primary)
MOD_ATT:N-ADJ (adipocytes,__SP__)
MOD_ATT:N-ADJ (protein,mutant)
MOD_ATT:N-ADJ (protein,__NODE__)
MOD_ATT:N-N (domain,DNA)
MOD_ATT:N-N (domain,bind)
COMP:V-N(In) (decrease,adipocytes)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,transcription)
COMP:N-N(of) (transcription,DNA)
MOD_POST:N-ADJ (transcription,endogenous)
COMP:ADJ-N(from) (endogenous,__NODE__)
MOD_ATT:N-ADJ (__NODE__,__SP__)