Validation pour Ingenuity300

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Ingenuity300

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Phrase 38 - PMID ?

In skeletal muscle cells , dominant negative mutant SP NODE protein ( deletion with its hinge domain mutated ) decreases expression of SP SREBP 1c [NODE] mRNA .

Non annotée
Je ne sais pas
Je n'ai pas trouvé d'analyse satisfaisante

Commentaires :

Analyse 0

                      +---------------------------------------------COMP:V-N(In)--------------------------------------------+                                                    
                      |         +-------------MOD_ATT:N-ADJ-------------+                                                   |                                                    
                      |         |        +---------MOD_ATT:N-ADJ--------+                                                   |          +-------------COMP:N-N(of)------------+   
                      |         |        |       +-----MOD_ATT:N-ADJ----+----------------------SUBJ:V-N---------------------+          |           +------MOD_ATT:N-ADJ------+   
        +MOD_ATT:N-ADJ+         |        |       |      +-MOD_ATT:N-ADJ-+          +----COMP:N-N(with)----+                 |          |           |          +-MOD_ATT:N-ADJ+   
        |       +MOD_A+         |        |       |      |       +MOD_ATT+---APPOS--+               +MOD_AT+SUBJ:V+          +--OBJ:V-N-+           |          |      +MOD_ATT+   
        |       |     |         |        |       |      |       |       |          |               |      |      |          |          |           |          |      |       |   
 In skeletal muscle cells , dominant negative mutant __SP__ __NODE__ protein ( deletion with its hinge domain mutated ) decreases expression of __SP__ SREBP 1c [__NODE__] mRNA .
MOD_ATT:N-ADJ (cell,skeletal)
MOD_ATT:N-N (cell,muscle)
MOD_ATT:N-ADJ (protein,dominant)
MOD_ATT:N-ADJ (protein,negative)
MOD_ATT:N-ADJ (protein,mutant)
MOD_ATT:N-ADJ (protein,__SP__)
MOD_ATT:N-ADJ (protein,__NODE__)
APPOS (protein,deletion)
COMP:N-N(with) (deletion,domain)
MOD_ATT:N-N (domain,hinge)
SUBJ:V_PASS-N (mutate,domain)
COMP:V-N(In) (decrease,cell)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,expression)
COMP:N-N(of) (expression,mRNA)
MOD_ATT:N-ADJ (mRNA,__SP__)
MOD_ATT:N-ADJ (mRNA,1c)
MOD_ATT:N-N (mRNA,[__NODE__])

Analyse 1

                      +---------------------------------------------COMP:V-N(In)--------------------------------------------+                                                    
                      |         +-------------MOD_ATT:N-ADJ-------------+                                                   |                                                    
                      |         |        +---------MOD_ATT:N-ADJ--------+                                                   |          +-------------COMP:N-N(of)------------+   
                      |         |        |       +-----MOD_ATT:N-ADJ----+----------------------SUBJ:V-N---------------------+          |           +------MOD_ATT:N-ADJ------+   
        +MOD_ATT:N-ADJ+         |        |       |      +-MOD_ATT:N-ADJ-+          +----COMP:N-N(with)----+                 |          |           |     +----MOD_ATT:N-N----+   
        |       +MOD_A+         |        |       |      |       +MOD_ATT+---APPOS--+               +MOD_AT+SUBJ:V+          +--OBJ:V-N-+           |     |           +MOD_ATT+   
        |       |     |         |        |       |      |       |       |          |               |      |      |          |          |           |     |           |       |   
 In skeletal muscle cells , dominant negative mutant __SP__ __NODE__ protein ( deletion with its hinge domain mutated ) decreases expression of __SP__ SREBP 1c [__NODE__] mRNA .
MOD_ATT:N-ADJ (cell,skeletal)
MOD_ATT:N-N (cell,muscle)
MOD_ATT:N-ADJ (protein,dominant)
MOD_ATT:N-ADJ (protein,negative)
MOD_ATT:N-ADJ (protein,mutant)
MOD_ATT:N-ADJ (protein,__SP__)
MOD_ATT:N-ADJ (protein,__NODE__)
APPOS (protein,deletion)
COMP:N-N(with) (deletion,domain)
MOD_ATT:N-N (domain,hinge)
SUBJ:V_PASS-N (mutate,domain)
COMP:V-N(In) (decrease,cell)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,expression)
COMP:N-N(of) (expression,mRNA)
MOD_ATT:N-ADJ (mRNA,__SP__)
MOD_ATT:N-N (mRNA,SREBP)
MOD_ATT:N-N (mRNA,[__NODE__])

Analyse 2

                      +---------------------------------------------COMP:V-N(In)--------------------------------------------+                                                    
                      |         +-------------MOD_ATT:N-ADJ-------------+                                                   |                                                    
                      |         |        +---------MOD_ATT:N-ADJ--------+----------------------SUBJ:V-N---------------------+          +-------------COMP:N-N(of)------------+   
                      |         |        |       +-----MOD_ATT:N-ADJ----+          +--------SUBJ:V_PASS-N--------+          |          |           +------MOD_ATT:N-ADJ------+   
        +MOD_ATT:N-ADJ+         |        |       |      +-MOD_ATT:N-ADJ-+          +----COMP:N-N(with)----+      |          |          |           |          +-MOD_ATT:N-ADJ+   
        |       +MOD_A+         |        |       |      |       +MOD_ATT+---APPOS--+               +MOD_AT+      |          +--OBJ:V-N-+           |          |      +MOD_ATT+   
        |       |     |         |        |       |      |       |       |          |               |      |      |          |          |           |          |      |       |   
 In skeletal muscle cells , dominant negative mutant __SP__ __NODE__ protein ( deletion with its hinge domain mutated ) decreases expression of __SP__ SREBP 1c [__NODE__] mRNA .
MOD_ATT:N-ADJ (cell,skeletal)
MOD_ATT:N-N (cell,muscle)
MOD_ATT:N-ADJ (protein,dominant)
MOD_ATT:N-ADJ (protein,negative)
MOD_ATT:N-ADJ (protein,mutant)
MOD_ATT:N-ADJ (protein,__SP__)
MOD_ATT:N-ADJ (protein,__NODE__)
APPOS (protein,deletion)
COMP:N-N(with) (deletion,domain)
MOD_ATT:N-N (domain,hinge)
SUBJ:V_PASS-N (mutate,deletion)
COMP:V-N(In) (decrease,cell)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,expression)
COMP:N-N(of) (expression,mRNA)
MOD_ATT:N-ADJ (mRNA,__SP__)
MOD_ATT:N-ADJ (mRNA,1c)
MOD_ATT:N-N (mRNA,[__NODE__])

Analyse 3

                      +---------------------------------------------COMP:V-N(In)--------------------------------------------+                                                    
                      |         +-------------MOD_ATT:N-ADJ-------------+                                                   |                                                    
                      |         |        +---------MOD_ATT:N-ADJ--------+----------------------SUBJ:V-N---------------------+          +-------------COMP:N-N(of)------------+   
                      |         |        |       +-----MOD_ATT:N-ADJ----+          +--------SUBJ:V_PASS-N--------+          |          |           +------MOD_ATT:N-ADJ------+   
        +MOD_ATT:N-ADJ+         |        |       |      +-MOD_ATT:N-ADJ-+          +----COMP:N-N(with)----+      |          |          |           |     +----MOD_ATT:N-N----+   
        |       +MOD_A+         |        |       |      |       +MOD_ATT+---APPOS--+               +MOD_AT+      |          +--OBJ:V-N-+           |     |           +MOD_ATT+   
        |       |     |         |        |       |      |       |       |          |               |      |      |          |          |           |     |           |       |   
 In skeletal muscle cells , dominant negative mutant __SP__ __NODE__ protein ( deletion with its hinge domain mutated ) decreases expression of __SP__ SREBP 1c [__NODE__] mRNA .
MOD_ATT:N-ADJ (cell,skeletal)
MOD_ATT:N-N (cell,muscle)
MOD_ATT:N-ADJ (protein,dominant)
MOD_ATT:N-ADJ (protein,negative)
MOD_ATT:N-ADJ (protein,mutant)
MOD_ATT:N-ADJ (protein,__SP__)
MOD_ATT:N-ADJ (protein,__NODE__)
APPOS (protein,deletion)
COMP:N-N(with) (deletion,domain)
MOD_ATT:N-N (domain,hinge)
SUBJ:V_PASS-N (mutate,deletion)
COMP:V-N(In) (decrease,cell)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,expression)
COMP:N-N(of) (expression,mRNA)
MOD_ATT:N-ADJ (mRNA,__SP__)
MOD_ATT:N-N (mRNA,SREBP)
MOD_ATT:N-N (mRNA,[__NODE__])

Analyse 4

                      +---------------------------------------------COMP:V-N(In)--------------------------------------------+                                                    
                      |         +-------------MOD_ATT:N-ADJ-------------+                                                   |                                                    
                      |         |        +---------MOD_ATT:N-ADJ--------+                                                   |          +-------------COMP:N-N(of)------------+   
                      |         |        |       +-----MOD_ATT:N-ADJ----+----------------------SUBJ:V-N---------------------+          |                 +----MOD_ATT:N-N----+   
        +MOD_ATT:N-ADJ+         |        |       |      +-MOD_ATT:N-ADJ-+          +----COMP:N-N(with)----+                 |          |                 |    +-MOD_ATT:N-ADJ+   
        |       +MOD_A+         |        |       |      |       +MOD_ATT+---APPOS--+               +MOD_AT+SUBJ:V+          +--OBJ:V-N-+                 |    |      +MOD_ATT+   
        |       |     |         |        |       |      |       |       |          |               |      |      |          |          |                 |    |      |       |   
 In skeletal muscle cells , dominant negative mutant __SP__ __NODE__ protein ( deletion with its hinge domain mutated ) decreases expression of __SP__ SREBP 1c [__NODE__] mRNA .
MOD_ATT:N-ADJ (cell,skeletal)
MOD_ATT:N-N (cell,muscle)
MOD_ATT:N-ADJ (protein,dominant)
MOD_ATT:N-ADJ (protein,negative)
MOD_ATT:N-ADJ (protein,mutant)
MOD_ATT:N-ADJ (protein,__SP__)
MOD_ATT:N-ADJ (protein,__NODE__)
APPOS (protein,deletion)
COMP:N-N(with) (deletion,domain)
MOD_ATT:N-N (domain,hinge)
SUBJ:V_PASS-N (mutate,domain)
COMP:V-N(In) (decrease,cell)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,expression)
COMP:N-N(of) (expression,mRNA)
MOD_ATT:N-N (mRNA,SREBP)
MOD_ATT:N-ADJ (mRNA,1c)
MOD_ATT:N-N (mRNA,[__NODE__])

Analyse 5

                      +---------------------------------------------COMP:V-N(In)--------------------------------------------+                                                    
                      |         +-------------MOD_ATT:N-ADJ-------------+                                                   |                                                    
                      |         |        +---------MOD_ATT:N-ADJ--------+----------------------SUBJ:V-N---------------------+          +-------------COMP:N-N(of)------------+   
                      |         |        |       +-----MOD_ATT:N-ADJ----+          +--------SUBJ:V_PASS-N--------+          |          |                 +----MOD_ATT:N-N----+   
        +MOD_ATT:N-ADJ+         |        |       |      +-MOD_ATT:N-ADJ-+          +----COMP:N-N(with)----+      |          |          |                 |    +-MOD_ATT:N-ADJ+   
        |       +MOD_A+         |        |       |      |       +MOD_ATT+---APPOS--+               +MOD_AT+      |          +--OBJ:V-N-+                 |    |      +MOD_ATT+   
        |       |     |         |        |       |      |       |       |          |               |      |      |          |          |                 |    |      |       |   
 In skeletal muscle cells , dominant negative mutant __SP__ __NODE__ protein ( deletion with its hinge domain mutated ) decreases expression of __SP__ SREBP 1c [__NODE__] mRNA .
MOD_ATT:N-ADJ (cell,skeletal)
MOD_ATT:N-N (cell,muscle)
MOD_ATT:N-ADJ (protein,dominant)
MOD_ATT:N-ADJ (protein,negative)
MOD_ATT:N-ADJ (protein,mutant)
MOD_ATT:N-ADJ (protein,__SP__)
MOD_ATT:N-ADJ (protein,__NODE__)
APPOS (protein,deletion)
COMP:N-N(with) (deletion,domain)
MOD_ATT:N-N (domain,hinge)
SUBJ:V_PASS-N (mutate,deletion)
COMP:V-N(In) (decrease,cell)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,expression)
COMP:N-N(of) (expression,mRNA)
MOD_ATT:N-N (mRNA,SREBP)
MOD_ATT:N-ADJ (mRNA,1c)
MOD_ATT:N-N (mRNA,[__NODE__])