In __SP__ hepatoma cells , 10E , octadecadienoic acid and 10E , octadecadienoic acid and 10Z , octadecadienoic acid and 9E , octadecadienoic acid and 9E , octadecadienoic acid and 9Z , octadecadienoic acid and 9Z , octadecadienoic acid and __NODE__ increase activation of __SP__ __NODE__ protein .