Interference of __SP__ __NODE__ mRNA in H1734 cells by siRNA and interference of __SP__ __NODE__ mRNA in H1734 cells by siRNA and interference of __SP__ __NODE__ mRNA in H1734 cells by siRNA and interference of __SP__ __NODE__ mRNA in H1734 cells by siRNA cause little or no change in activation of __SP__ __NODE__ protein(s) in H1734 cells that is increased by __NODE__ in culture medium .