In T lymphocytes expressing __SP__ __NODE__ from mutant __SP__ with a homozygous knockout of __SP__ Rag 2 [__NODE__] and overproducing 2C __NODE__ , priming of T lymphocytes expressing __SP__ __NODE__ from mutant __SP__ with a homozygous knockout of __SP__ Rag 2 [__NODE__] and overproducing 2C __NODE__ increases expression of __SP__ __NODE__ .