__NODE__ in mutant __SP__ with a homozygous knockout of __SP__ __NODE__ and __SP__ __NODE__ increases expression of __SP__ __NODE__ mRNA in liver from mutant __SP__ with a homozygous knockout of __SP__ __NODE__ and __SP__ __NODE__ that is increased by PR835 in mutant __SP__ with a homozygous knockout of __SP__ __NODE__ and __SP__ __NODE__ .