+---------OBJ:V-N---------+                       
     +MOD_ATT+SUBJ:V-N+           +MOD_ATT:N-ADJ+COMP:N-N(of)+          
     |       |        |           |             |            |          
 __NODE__ protein mediates transcriptional activation of __NODE__ gene .
MOD_ATT:N-ADJ (protein,__NODE__)
SUBJ:V-N (mediate,protein)
OBJ:V-N (mediate,activation)
MOD_ATT:N-ADJ (activation,transcriptional)
COMP:N-N(of) (activation,__NODE__)