+---COMP:N-N(of)---+    
     +MOD_AT+-SUBJ:V-N+-COMP:V-N(up)+           +MOD_AT+    
     |      |         |             |           |      |    
 PGC 1 [__NODE__] increases up regulation of nuclear genes .
MOD_ATT:N-N ([__NODE__],1)
SUBJ:V-N (increase,[__NODE__])
COMP:V-N(up) (increase,regulation)
COMP:N-N(of) (regulation,gene)
MOD_ATT:N-ADJ (gene,nuclear)