In Hela cells treated with agonist anti __SP__ Apo 1 [__NODE__] protein antibody and with cycloheximide and with zVAD FMK and overproducing __SP__ __NODE__ protein , a protein fragment ( 87 501 ) from __NODE__ protein in Hela cells treated with agonist anti __SP__ Apo 1 [__NODE__] protein antibody and with cycloheximide and with zVAD FMK and overproducing __SP__ __NODE__ protein decreases activation of a luciferase reporter gene with a synthetic promoter that has a __NODE__ protein protein binding site .