+----------------COMP:V-N(In)---------------+                                   
         |             +-----------SUBJ:V-N----------+                                   
         |             +----COMP:N-N(of)----+        |         +----COMP:N-N(of)---+     
         |             |            +MOD_ATT+        +-OBJ:V-N-+           +MOD_ATT+     
         |             |            |       |        |         |           |       |     
 In macrophages , activation of __NODE__ protein decreases activity of __NODE__ protein .
COMP:N-N(of) (activation,protein)
MOD_ATT:N-ADJ (protein,__NODE__)
COMP:V-N(In) (decrease,macrophage)
SUBJ:V-N (decrease,activation)
OBJ:V-N (decrease,activity)
COMP:N-N(of) (activity,protein)
MOD_ATT:N-ADJ (protein,__NODE__)