In __SP__ , a protein chimera composed of __SP__ LexA protein and of a protein fragment ( 198 462 ) from __SP__ __NODE__ protein in __SP__ and a protein chimera composed of a protein fragment ( 169 461 ) from __SP__ __NODE__ protein and of a protein fragment containing a B42 transcriptional activation domain in __SP__ increase transcription of beta galactosidase reporter gene containing a LexA DNA binding site .