Mutant __SP__ __NODE__ protein ( N terminal truncation 1 1552 with its Ced 4 homology domain deleted and with its DED recruiting domain retained ) in Hela cells treated with agonist anti __NODE__ protein antibody and with cycloheximide and overproducing __SP__ __NODE__ protein decreases apoptosis of Hela cells treated with agonist anti __NODE__ protein antibody and with cycloheximide and overproducing __SP__ __NODE__ protein in cell culture .