Validation pour Ingenuity001

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Ingenuity001

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Phrase 70 - PMID ?

25 hydroxycholesterol in cell culture and NODE in cell culture cause little or no change in cleavage of SP NODE protein in CHO 7 cells not expressing hamster NODE protein and overproducing a protein chimera composed of mutant hamster NODE protein ( C terminal truncation 998 End with its transmembrane domain deleted ) and of a protein fragment ( aa sequence KDEL ) and SP NODE protein .

Non annotée
Je ne sais pas
Je n'ai pas trouvé d'analyse satisfaisante

Commentaires :

Analyse 0

  +------------------------------SUBJ:V-N-----------------------------+-----------------------COMP:V-N(in)----------------------+                                                                                                                                                                                                                                                                                               
  |                                            +-------SUBJ:V-N-------+                              +--------MOD_ATT:N-N-------+               +-----------------------SUBJ:V-N----------------------+                    +------------COMP:N-N(of)-----------+       +---------APPOS--------+------------------------------COMP:N-N(with)------------------------------+                                                      
  +----------COMP:N-N(in)---------+            +--COMP:N-N(in)-+      +------OBJ:V-N------+          |          +-MOD_ATT:N-ADJ-+--COMP:N-N(in)-+            +---------OBJ:V-N---------+              +-------OBJ:V-N------+                   +-MOD_ATT:N-ADJ-+       |      +--MOD_ATT:N-N--+-------------COMP:N-N(with)------------+                                  +--------APPOS-------+           +-MOD_ATT:N-ADJ-+     
  |                         +MOD_A+            |         +MOD_A+      +OBJ:V-+            |          |          |       +MOD_ATT+           +MOD+SUBJ+       |        +---MOD_ATT:N-N--+              |            +MOD_ATT+SUBJ:V_P+          |      +MOD_ATT:+       |      |     +MOD_ATT:N+      +MOD+                 +MOD_ATT:N-+SUBJ:V+                  +MOD_ATT:+       +MOD_A+MOD_AT+           |       +MOD_ATT+     
  |                         |     |            |         |     |      |      |            |          |          |       |       |           |   |    |       |        |                |              |            |       |        |          |      |        |       |      |     |         |      |   |                 |          |      |                  |        |       |     |      |           |       |       |     
 25 hydroxycholesterol in cell culture and __NODE__ in cell culture cause little or no change in cleavage of __SP__ __NODE__ protein in CHO 7 cells not expressing hamster __NODE__ protein and overproducing a protein chimera composed of mutant hamster __NODE__ protein ( C terminal truncation 998 End with its transmembrane domain deleted ) and of a protein fragment ( aa sequence KDEL ) and __SP__ __NODE__ protein .
COMP:N-N(in) (@card@,culture)
MOD_ATT:N-N (culture,cell)
COMP:N-N(in) (__NODE__,culture)
MOD_ATT:N-N (culture,cell)
SUBJ:V-N (cause,@card@)
SUBJ:V-N (cause,__NODE__)
OBJ:V-N (cause,little)
OBJ:V-N (cause,change)
COMP:V-N(in) (cause,protein)
MOD_ATT:N-N (protein,cleavage)
MOD_ATT:N-ADJ (protein,__SP__)
MOD_ATT:N-ADJ (protein,__NODE__)
COMP:N-N(in) (protein,cell)
MOD_ATT:N-N (cell,7)
SUBJ:V-N (not,cell)
OBJ:V-N (express,protein)
MOD_ATT:N-N (protein,hamster)
SUBJ:V-N (overproduce,cell)
OBJ:V-N (overproduce,chimera)
MOD_ATT:N-N (chimera,protein)
COMP:N-N(of) (chimera,__NODE__)
SUBJ:V_PASS-N (compose,chimera)
MOD_ATT:N-ADJ (__NODE__,mutant)
MOD_ATT:N-N (__NODE__,hamster)
APPOS (protein,truncation)
MOD_ATT:N-N (truncation,C)
MOD_ATT:N-N (truncation,terminal)
COMP:N-N(with) (truncation,domain)
COMP:N-N(with) (truncation,fragment)
MOD_ATT:N-ADJ (end,@card@)
MOD_ATT:N-ADJ (domain,transmembrane)
SUBJ:V_PASS-N (delete,domain)
MOD_ATT:N-N (fragment,protein)
APPOS (fragment,KDEL)
MOD_ATT:N-N (sequence,aa)
MOD_ATT:N-N (KDEL,sequence)
MOD_ATT:N-ADJ (protein,__SP__)
MOD_ATT:N-ADJ (protein,__NODE__)

Analyse 1

             +------------------------SUBJ:V-N------------------------+-----------------------COMP:V-N(in)----------------------+                                                                                                                                                                                                                                                                                               
             |                                 +-------SUBJ:V-N-------+                              +--------MOD_ATT:N-N-------+------SUBJ:V-N------+                                                                     +----------------COMP:N-N(of)---------------+---------APPOS--------+------------------------------COMP:N-N(with)------------------------------+                                                      
             +----COMP:N-N(in)----+            +--COMP:N-N(in)-+      +------OBJ:V-N------+          |          +-MOD_ATT:N-ADJ-+--COMP:N-N(in)-+    |       +---------OBJ:V-N---------+              +-------OBJ:V-N------+                   +-MOD_ATT:N-ADJ-+       |      +--MOD_ATT:N-N--+-------------COMP:N-N(with)------------+                                  +--------APPOS-------+           +-MOD_ATT:N-ADJ-+     
             |              +MOD_A+            |         +MOD_A+      +OBJ:V-+            |          |          |       +MOD_ATT+           +MOD+    |       |                 +MOD_ATT+              |            +MOD_ATT+SUBJ:V_P+          |      +MOD_ATT:+       |      |     +MOD_ATT:N+      +MOD+                 +MOD_ATT:N-+SUBJ:V+                  +MOD_ATT:+       +MOD_A+MOD_AT+           |       +MOD_ATT+     
             |              |     |            |         |     |      |      |            |          |          |       |       |           |   |    |       |                 |       |              |            |       |        |          |      |        |       |      |     |         |      |   |                 |          |      |                  |        |       |     |      |           |       |       |     
 25 hydroxycholesterol in cell culture and __NODE__ in cell culture cause little or no change in cleavage of __SP__ __NODE__ protein in CHO 7 cells not expressing hamster __NODE__ protein and overproducing a protein chimera composed of mutant hamster __NODE__ protein ( C terminal truncation 998 End with its transmembrane domain deleted ) and of a protein fragment ( aa sequence KDEL ) and __SP__ __NODE__ protein .
COMP:N-N(in) (hydroxycholesterol,culture)
MOD_ATT:N-N (culture,cell)
COMP:N-N(in) (__NODE__,culture)
MOD_ATT:N-N (culture,cell)
SUBJ:V-N (cause,hydroxycholesterol)
SUBJ:V-N (cause,__NODE__)
OBJ:V-N (cause,little)
OBJ:V-N (cause,change)
COMP:V-N(in) (cause,protein)
MOD_ATT:N-N (protein,cleavage)
MOD_ATT:N-ADJ (protein,__SP__)
MOD_ATT:N-ADJ (protein,__NODE__)
COMP:N-N(in) (protein,cell)
MOD_ATT:N-N (cell,7)
SUBJ:V-N (not,protein)
OBJ:V-N (express,protein)
MOD_ATT:N-ADJ (protein,__NODE__)
OBJ:V-N (overproduce,chimera)
MOD_ATT:N-N (chimera,protein)
COMP:N-N(of) (chimera,protein)
SUBJ:V_PASS-N (compose,chimera)
MOD_ATT:N-ADJ (__NODE__,mutant)
MOD_ATT:N-N (__NODE__,hamster)
APPOS (protein,truncation)
MOD_ATT:N-N (truncation,C)
MOD_ATT:N-N (truncation,terminal)
COMP:N-N(with) (truncation,domain)
COMP:N-N(with) (truncation,fragment)
MOD_ATT:N-ADJ (end,@card@)
MOD_ATT:N-ADJ (domain,transmembrane)
SUBJ:V_PASS-N (delete,domain)
MOD_ATT:N-N (fragment,protein)
APPOS (fragment,KDEL)
MOD_ATT:N-N (sequence,aa)
MOD_ATT:N-N (KDEL,sequence)
MOD_ATT:N-ADJ (protein,__SP__)
MOD_ATT:N-ADJ (protein,__NODE__)