Binding of a mutant DNA fragment ( A?C C?T C?T G?T G?T T?C ) ( 5 ' GGGTTTGCTTTTTCTCTCCGGGTAAATTCGAAGG 3 ' containing a NRRE 1 from __SP__ __NODE__ gene and a protein protein complex consisting of __SP__ __NODE__ and of __SP__ __NODE__ does not occur in cell free system .