Binding of a mutant DNA fragment ( 124 96 ) ( A 117C A 116C A 115C A 114G C 113G A 112G T 105G T 104G T 103G T 102G G 101T with its __NODE__ response sequence mutated ) from __SP__ __NODE__ gene and __SP__ __NODE__ protein(s) does not occur in nuclear extract from H 4 II E cells .