In a cell free system , the affinity of binding of a DNA fragment with a DNA endogenous promoter from the __SP__ __NODE__ gene that has a __NODE__ response element and a protein protein complex consisting of __SP__ __NODE__ and of __SP__ __NODE__ is the same as the affinity of binding of a DNA fragment with a DNA endogenous promoter from the __SP__ __NODE__ gene that has a __NODE__ response element and a protein protein complex consisting of __SP__ __NODE__ and of __SP__ __NODE__ .