Validation pour Ingenuity294

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Ingenuity294

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Phrase 35 - PMID ?

In primary vascular smooth muscle cells from male adult SP thoracic aorta , NODE protein and NODE protein decrease activity of a luciferase reporter gene with a DNA endogenous promoter ( 1153 46 ) from the mutant SP NODE gene ( A 922G A 921C C 916A C 915G with its PPRE mutated ) that is increased by NODE protein .

Non annotée
Je ne sais pas
Je n'ai pas trouvé d'analyse satisfaisante

Commentaires :

Analyse 0

       +--------MOD_ATT:N-ADJ--------+                                                                                              +-----------------------COMP:N-N(with)-----------------------+            +------------COMP:N-N(from)-----------+                                                                                               
       |        +----MOD_ATT:N-ADJ---+----COMP:N-N(from)----+                                                                       +----------COMP:N-N(of)---------+                            |            |               +----MOD_ATT:N-ADJ----+                      +----------OBJ:V-N---------+                                             
       |        |       +MOD_ATT:N-AD+          +MOD_ATT:N-N+       +------MOD_ATT:N-ADJ-----+-----------SUBJ:V-N----------+        |              +---MOD_ATT:N-N--+          +---MOD_ATT:N-N---+            |               |      +-MOD_ATT:N-ADJ+---APPOS---+   +MOD_AT+      +------SUBJ:V-N-----+                  +--COMP:V_PASS-N(by)-+     
       |        |       |      +MOD_A+          |    +MOD_AT+       |                +MOD_ATT+            +MOD_ATT+SUBJ:V-N+-OBJ:V-N+              |         +MOD_AT+          |       +MOD_ATT:N+--APPOS-+   |               |      |       +MOD_AT+    +MOD+MO+   |  +MOD+  +MOD+COMP:N-N(with+     |                  |            +MOD_ATT+     
       |        |       |      |     |          |    |      |       |                |       |            |       |        |        |              |         |      |          |       |         |        |   |               |      |       |      |    |   |  |   |  |   |  |   |             |     |                  |            |       |     
 In primary vascular smooth muscle cells from male adult __SP__ thoracic aorta , __NODE__ protein and __NODE__ protein decrease activity of a luciferase reporter gene with a DNA endogenous promoter ( 1153 46 ) from the mutant __SP__ __NODE__ gene ( A 922G A 921C C 916A C 915G with its PPRE mutated ) that is increased by __NODE__ protein .
MOD_ATT:N-ADJ (cell,primary)
MOD_ATT:N-ADJ (cell,vascular)
MOD_ATT:N-ADJ (cell,smooth)
MOD_ATT:N-N (cell,muscle)
COMP:N-N(from) (cell,__SP__)
MOD_ATT:N-N (__SP__,male)
MOD_ATT:N-N (__SP__,adult)
MOD_ATT:N-ADJ (protein,thoracic)
MOD_ATT:N-ADJ (protein,__NODE__)
MOD_ATT:N-ADJ (protein,__NODE__)
SUBJ:V-N (decrease,protein)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,activity)
COMP:N-N(of) (activity,gene)
COMP:N-N(with) (activity,promoter)
MOD_ATT:N-N (gene,luciferase)
MOD_ATT:N-N (gene,reporter)
MOD_ATT:N-N (promoter,DNA)
MOD_ATT:N-ADJ (promoter,endogenous)
APPOS (promoter,@card@)
COMP:N-N(from) (@card@,gene)
MOD_ATT:N-ADJ (gene,mutant)
MOD_ATT:N-ADJ (gene,__SP__)
MOD_ATT:N-ADJ (gene,__NODE__)
APPOS (gene,a)
MOD_ATT:N-N (922G,a)
MOD_ATT:N-N (a,922G)
MOD_ATT:N-ADJ (916A,921C)
MOD_ATT:N-N (916A,C)
MOD_ATT:N-N (915G,C)
COMP:N-N(with) (915G,PPRE)
OBJ:V-N (mutate,916A)
SUBJ:V-N (mutate,915G)
COMP:V_PASS-N(by) (increase,protein)
MOD_ATT:N-ADJ (protein,__NODE__)

Analyse 1

       +---------MOD_ATT:N-N---------+                                                                                              +-----------------------COMP:N-N(with)-----------------------+            +------------COMP:N-N(from)-----------+                                                                                               
       |        +----MOD_ATT:N-ADJ---+----COMP:N-N(from)----+                                                                       +----------COMP:N-N(of)---------+                            |            |               +----MOD_ATT:N-ADJ----+           +MOD_ATT:N-+----------OBJ:V-N---------+                                             
       |        |       +MOD_ATT:N-AD+          +MOD_ATT:N-N+       +------MOD_ATT:N-ADJ-----+-----------SUBJ:V-N----------+        |              +---MOD_ATT:N-N--+          +---MOD_ATT:N-N---+            |               |      +-MOD_ATT:N-ADJ+--APPOS-+  |   +MOD_AT+      +------SUBJ:V-N-----+--------------COMP:V-N(by)-------------+     
       |        |       |      +MOD_A+          |    +MOD_AT+       |                +MOD_ATT+            +MOD_ATT+SUBJ:V-N+-OBJ:V-N+              |         +MOD_AT+          |       +MOD_ATT:N+--APPOS-+   |               |      |       +MOD_AT+    +MOD+  |   |  +MOD+  +MOD+COMP:N-N(with+     |                               +MOD_ATT+     
       |        |       |      |     |          |    |      |       |                |       |            |       |        |        |              |         |      |          |       |         |        |   |               |      |       |      |    |   |  |   |  |   |  |   |             |     |                               |       |     
 In primary vascular smooth muscle cells from male adult __SP__ thoracic aorta , __NODE__ protein and __NODE__ protein decrease activity of a luciferase reporter gene with a DNA endogenous promoter ( 1153 46 ) from the mutant __SP__ __NODE__ gene ( A 922G A 921C C 916A C 915G with its PPRE mutated ) that is increased by __NODE__ protein .
MOD_ATT:N-N (cell,primary)
MOD_ATT:N-ADJ (cell,vascular)
MOD_ATT:N-ADJ (cell,smooth)
MOD_ATT:N-N (cell,muscle)
COMP:N-N(from) (cell,__SP__)
MOD_ATT:N-N (__SP__,male)
MOD_ATT:N-N (__SP__,adult)
MOD_ATT:N-ADJ (protein,thoracic)
MOD_ATT:N-ADJ (protein,__NODE__)
MOD_ATT:N-ADJ (protein,__NODE__)
SUBJ:V-N (decrease,protein)
SUBJ:V-N (decrease,protein)
OBJ:V-N (decrease,activity)
COMP:N-N(of) (activity,gene)
COMP:N-N(with) (activity,promoter)
MOD_ATT:N-N (gene,luciferase)
MOD_ATT:N-N (gene,reporter)
MOD_ATT:N-N (promoter,DNA)
MOD_ATT:N-ADJ (promoter,endogenous)
APPOS (promoter,@card@)
COMP:N-N(from) (@card@,gene)
MOD_ATT:N-ADJ (gene,mutant)
MOD_ATT:N-ADJ (gene,__SP__)
MOD_ATT:N-ADJ (gene,__NODE__)
APPOS (gene,922G)
MOD_ATT:N-N (922G,a)
MOD_ATT:N-N (916A,a)
MOD_ATT:N-ADJ (916A,921C)
MOD_ATT:N-N (916A,C)
MOD_ATT:N-N (915G,C)
COMP:N-N(with) (915G,PPRE)
OBJ:V-N (mutate,916A)
SUBJ:V-N (mutate,915G)
COMP:V-N(by) (mutate,protein)
MOD_ATT:N-ADJ (protein,__NODE__)

Analyse 2

       +---------MOD_ATT:N-N---------+                                                       +-----------------------------COMP:N-N(of)-----------------------------+                                         +------------COMP:N-N(from)-----------+        +-MOD_ATT:N-N-+                                                                        
       |        +----MOD_ATT:N-ADJ---+----COMP:N-N(from)----+                                |            +------MOD_ATT:N-ADJ------+----------COMP:N-N(of)---------+-------COMP:N-N(with)-------+            |               +----MOD_ATT:N-ADJ----+        |  +MOD_ATT:N-+----------OBJ:V-N---------+                                             
       |        |       +MOD_ATT:N-AD+          +MOD_ATT:N-N+--------------APPOS-------------+            |       +---MOD_ATT:N-N---+              +---MOD_ATT:N-N--+          +---MOD_ATT:N-N---+            |               |      +-MOD_ATT:N-ADJ+        |  |   +MOD_AT+      +------SUBJ:V-N-----+                  +--COMP:V_PASS-N(by)-+     
       |        |       |      +MOD_A+          |    +MOD_AT+                        +MOD_ATT+            |       |        +MOD_ATT:+              |         +MOD_AT+          |       +MOD_ATT:N+--APPOS-+   |               |      |       +MOD_AT+APPO+   |  |   |  +MOD+  +MOD+COMP:N-N(with+     |                  |            +MOD_ATT+     
       |        |       |      |     |          |    |      |                        |       |            |       |        |        |              |         |      |          |       |         |        |   |               |      |       |      |    |   |  |   |  |   |  |   |             |     |                  |            |       |     
 In primary vascular smooth muscle cells from male adult __SP__ thoracic aorta , __NODE__ protein and __NODE__ protein decrease activity of a luciferase reporter gene with a DNA endogenous promoter ( 1153 46 ) from the mutant __SP__ __NODE__ gene ( A 922G A 921C C 916A C 915G with its PPRE mutated ) that is increased by __NODE__ protein .
MOD_ATT:N-N (cell,primary)
MOD_ATT:N-ADJ (cell,vascular)
MOD_ATT:N-ADJ (cell,smooth)
MOD_ATT:N-N (cell,muscle)
COMP:N-N(from) (cell,__SP__)
MOD_ATT:N-N (__SP__,male)
MOD_ATT:N-N (__SP__,adult)
APPOS (__SP__,protein)
MOD_ATT:N-ADJ (protein,__NODE__)
COMP:N-N(of) (protein,gene)
MOD_ATT:N-ADJ (activity,__NODE__)
MOD_ATT:N-N (activity,protein)
MOD_ATT:N-N (activity,decrease)
COMP:N-N(of) (activity,gene)
MOD_ATT:N-N (gene,luciferase)
MOD_ATT:N-N (gene,reporter)
COMP:N-N(with) (gene,promoter)
MOD_ATT:N-N (promoter,DNA)
MOD_ATT:N-ADJ (promoter,endogenous)
APPOS (promoter,@card@)
COMP:N-N(from) (@card@,gene)
MOD_ATT:N-ADJ (gene,mutant)
MOD_ATT:N-ADJ (gene,__SP__)
MOD_ATT:N-ADJ (gene,__NODE__)
APPOS (gene,a)
MOD_ATT:N-N (916A,922G)
MOD_ATT:N-N (916A,a)
MOD_ATT:N-ADJ (916A,921C)
MOD_ATT:N-N (916A,C)
MOD_ATT:N-N (915G,C)
COMP:N-N(with) (915G,PPRE)
OBJ:V-N (mutate,916A)
SUBJ:V-N (mutate,915G)
COMP:V_PASS-N(by) (increase,protein)
MOD_ATT:N-ADJ (protein,__NODE__)

Analyse 3

                                                            +--------------------------------OBJ:V-N--------------------------------+                                                                         +------------COMP:N-N(from)-----------+                                                                                               
       +-----MOD_ATT:N-ADJ-----+                            +-------------OBJ:V-N------------+            +------MOD_ATT:N-ADJ------+----------COMP:N-N(of)---------+-------COMP:N-N(with)-------+            |               +----MOD_ATT:N-ADJ----+                      +----------OBJ:V-N---------+                                             
       |        +-MOD_ATT:N-ADJ+--------COMP:V-N(In)--------+       +------MOD_ATT:N-ADJ-----+            |       +---MOD_ATT:N-N---+              +---MOD_ATT:N-N--+          +---MOD_ATT:N-N---+            |               |      +-MOD_ATT:N-ADJ+---APPOS---+   +MOD_AT+      +------SUBJ:V-N-----+--------------COMP:V-N(by)-------------+     
       |        |       +MOD_AT+     +-------SUBJ:V-N-------+       |                +MOD_ATT+            |       |        +MOD_ATT:+              |         +MOD_AT+          |       +MOD_ATT:N+----APPOS---+               |      |       +MOD_AT+    +MOD+MO+   |  +MOD+  +MOD+COMP:N-N(with+     |                               +MOD_ATT+     
       |        |       |      |     |                      |       |                |       |            |       |        |        |              |         |      |          |       |         |            |               |      |       |      |    |   |  |   |  |   |  |   |             |     |                               |       |     
 In primary vascular smooth muscle cells from male adult __SP__ thoracic aorta , __NODE__ protein and __NODE__ protein decrease activity of a luciferase reporter gene with a DNA endogenous promoter ( 1153 46 ) from the mutant __SP__ __NODE__ gene ( A 922G A 921C C 916A C 915G with its PPRE mutated ) that is increased by __NODE__ protein .
MOD_ATT:N-ADJ (muscle,primary)
MOD_ATT:N-ADJ (muscle,vascular)
MOD_ATT:N-ADJ (muscle,smooth)
COMP:V-N(In) (__SP__,muscle)
SUBJ:V-N (__SP__,cell)
OBJ:V-N (__SP__,protein)
OBJ:V-N (__SP__,activity)
MOD_ATT:N-ADJ (protein,thoracic)
MOD_ATT:N-ADJ (protein,__NODE__)
MOD_ATT:N-ADJ (activity,__NODE__)
MOD_ATT:N-N (activity,protein)
MOD_ATT:N-N (activity,decrease)
COMP:N-N(of) (activity,gene)
MOD_ATT:N-N (gene,luciferase)
MOD_ATT:N-N (gene,reporter)
COMP:N-N(with) (gene,promoter)
MOD_ATT:N-N (promoter,DNA)
MOD_ATT:N-ADJ (promoter,endogenous)
APPOS (promoter,@card@)
COMP:N-N(from) (@card@,gene)
MOD_ATT:N-ADJ (gene,mutant)
MOD_ATT:N-ADJ (gene,__SP__)
MOD_ATT:N-ADJ (gene,__NODE__)
APPOS (gene,a)
MOD_ATT:N-N (922G,a)
MOD_ATT:N-N (a,922G)
MOD_ATT:N-ADJ (916A,921C)
MOD_ATT:N-N (916A,C)
MOD_ATT:N-N (915G,C)
COMP:N-N(with) (915G,PPRE)
OBJ:V-N (mutate,916A)
SUBJ:V-N (mutate,915G)
COMP:V-N(by) (mutate,protein)
MOD_ATT:N-ADJ (protein,__NODE__)