Mutant __SP__ __NODE__ gene ( heterozygous knockout ) in mutant __SP__ with a homozygous knockout of __SP__ __NODE__ decreases accumulation of macrophages in lesioned aortic arch from mutant __SP__ with a homozygous knockout of __SP__ __NODE__ that is increased by high __NODE__ diet ( with a treatment period of 2 months ) of mutant __SP__ with a homozygous knockout of __SP__ __NODE__ .