Mutant __SP__ __NODE__ gene ( homozygous knockout ) in male 12 week old __SP__ increases phosphorylation of __SP__ __NODE__ protein(s) in __NODE__ muscle fibers from gastrocnemius of male 12 week old __SP__ to phosphorylated ( T172 ) __SP__ __NODE__ protein(s) in __NODE__ muscle fibers from gastrocnemius of male 12 week old __SP__ .