Mutant __SP__ __NODE__ protein ( C terminal truncation 1553 End with its DED recruiting domain deleted and with its Ced 4 homology domain retained N terminal truncation 1 855 with its DED recruiting domain deleted and with its Ced 4 homology domain retained ) in cycloheximide treated Hela cells overproducing __SP__ __NODE__ protein causes little or no change in apoptosis of cycloheximide treated Hela cells overproducing __SP__ __NODE__ protein in cell culture .