Mutant __SP__ __NODE__ protein ( C terminal truncation 1553 End with its DED recruiting domain deleted and with its Ced 4 homology domain retained N terminal truncation 1 855 with its DED recruiting domain deleted and with its Ced 4 homology domain retained ) in staurosporine treated Hela cells overproducing __SP__ __NODE__ protein and mutant __SP__ __NODE__ protein ( N terminal truncation 1 1552 with its Ced 4 homology domain deleted and with its DED recruiting domain retained ) in staurosporine treated Hela cells overproducing __SP__ __NODE__ protein cause little or no change in apoptosis of staurosporine treated Hela cells overproducing __SP__ __NODE__ protein in cell culture .