Mutant __SP__ __NODE__ protein ( C terminal truncation 1553 End with its DED recruiting domain deleted and with its Ced 4 homology domain retained N terminal truncation 1 855 with its DED recruiting domain deleted and with its Ced 4 homology domain retained ) in Hela cells treated with cycloheximide and with __NODE__ protein and overproducing __SP__ __NODE__ protein and mutant __SP__ __NODE__ protein ( N terminal truncation 1 1552 with its Ced 4 homology domain deleted and with its DED recruiting domain retained ) in Hela cells treated with cycloheximide and with __NODE__ protein and overproducing __SP__ __NODE__ protein decrease apoptosis of Hela cells treated with cycloheximide and with __NODE__ protein and overproducing __SP__ __NODE__ protein in cell culture .