In nuclear extract from Hela cells , binding of __SP__ __NODE__ gamma protein(s) and a DNA fragment ( 138 123 ) containing a __NODE__ binding site from __NODE__ gene(s) is the same as binding of __SP__ __NODE__ gamma protein(s) and a mutant DNA fragment ( 138 123 ) ( C 124A ) containing a __NODE__ binding site from __NODE__ gene(s) .