In a system of purified components , the affinity of binding of __SP__ Srebp 1a [__NODE__] protein and __NODE__ regulatory element 3 ( 5 ' TGGATGTGTCATCTCATATCCAGA 3 ' from __SP__ __NODE__ gene is greater than the affinity of binding of E box element from __SP__ __NODE__ gene and __SP__ Srebp 1a [__NODE__] protein .