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Ingenuity190

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Phrase 69 - PMID ?

In a system of purified components , vitamin D increases binding of a DNA fragment ( AGCTCAGGTCAAGGAGGTCAG ) with a DNA endogenous promoter that has a Vitamin D response element and __SP__ __NODE__ and __NODE__ protein and a protein protein complex consisting of mutant __NODE__ ( C terminal truncation with its AF 2 transcription activation domain deleted ) and of mutant __NODE__ ( C terminal truncation with its AF 2 transcription activation domain deleted ) .


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Analyse 0 
                                                                                                                                                   +---------------------------------------------OBJ:V-N---------------------------------------------+                                                                                                                                                                                                                          
                                                                                                                                                   +------------------------------OBJ:V-N------------------------------+                             |                                                    +-----------------COMP:N-N(with)----------------+                                                      +-----------------COMP:N-N(with)----------------+              
                              +--------APPOS--------+                                                                                              +----------OBJ:V-N---------+           +--------MOD_ATT:N-ADJ-------+                             |                             +---------APPOS--------+                 +---------MOD_ATT:N-N---------+                               +---------APPOS--------+                 +---------MOD_ATT:N-N---------+              
         +----COMP:N-N(of)----+          +MOD_ATT:N-+        +-----OBJ:V-N-----+                                      +---MOD_ATT:N-N---+          |            +-MOD_ATT:N-N-+           |       +----MOD_ATT:N-ADJ---+             +--MOD_ATT:N-N--+         +----COMP:N-N(of)---+      +--MOD_ATT:N-N--+                 |       +-----MOD_ATT:N-N-----+----------COMP:N-N(of)---------+      +--MOD_ATT:N-N--+                 |       +-----MOD_ATT:N-N-----+              
         |          +MOD_ATT:N+          |    +MOD_A+SUBJ:V-N+          +MOD_AT+------APPOS-----+                     |       +MOD_ATT:N+-SUBJ:V-N-+            |     +MOD_ATT+           |       |            +MOD_ATT+             |       +MOD_ATT+-SUBJ:V-N+           +MOD_ATT+      |     +MOD_ATT:N+                 |       |            +MOD_ATT:+SUBJ:V+                +MOD_ATT+      |     +MOD_ATT:N+                 |       |            +MOD_ATT:+SUBJ:V+       
         |          |         |          |    |     |        |          |      |                |                     |       |         |          |            |     |       |           |       |            |       |             |       |       |         |           |       |      |     |         |                 |       |            |        |      |                |       |      |     |         |                 |       |            |        |      |       
 In a system of purified components , vitamin D increases binding of a DNA fragment ( AGCTCAGGTCAAGGAGGTCAG ) with a DNA endogenous promoter that has a Vitamin D response element and __SP__ __NODE__ and __NODE__ protein and a protein protein complex consisting of mutant __NODE__ ( C terminal truncation with its AF 2 transcription activation domain deleted ) and of mutant __NODE__ ( C terminal truncation with its AF 2 transcription activation domain deleted ) .
COMP:N-N(of) (system,component)
MOD_ATT:N-ADJ (component,purify)
APPOS (component,increase)
MOD_ATT:N-N (increase,vitamin)
MOD_ATT:N-N (increase,D)
SUBJ:V-N (bind,increase)
OBJ:V-N (bind,fragment)
MOD_ATT:N-N (fragment,DNA)
APPOS (fragment,AGCTCAGGTCAAGGAGGTCAG)
MOD_ATT:N-N (promoter,DNA)
MOD_ATT:N-ADJ (promoter,endogenous)
SUBJ:V-N (have,promoter)
OBJ:V-N (have,element)
OBJ:V-N (have,protein)
OBJ:V-N (have,complex)
MOD_ATT:N-N (element,D)
MOD_ATT:N-N (element,response)
MOD_ATT:N-ADJ (protein,__SP__)
MOD_ATT:N-ADJ (protein,__NODE__)
MOD_ATT:N-ADJ (protein,__NODE__)
MOD_ATT:N-N (complex,protein)
MOD_ATT:N-N (complex,protein)
SUBJ:V-N (consist,complex)
COMP:N-N(of) (consist,__NODE__)
MOD_ATT:N-ADJ (__NODE__,mutant)
APPOS (__NODE__,truncation)
MOD_ATT:N-N (truncation,C)
MOD_ATT:N-ADJ (truncation,terminal)
COMP:N-N(with) (truncation,domain)
MOD_ATT:N-N (domain,2)
MOD_ATT:N-N (domain,transcription)
MOD_ATT:N-N (domain,activation)
COMP:N-N(of) (domain,__NODE__)
SUBJ:V_PASS-N (delete,domain)
MOD_ATT:N-ADJ (__NODE__,mutant)
APPOS (__NODE__,truncation)
MOD_ATT:N-N (truncation,C)
MOD_ATT:N-ADJ (truncation,terminal)
COMP:N-N(with) (truncation,domain)
MOD_ATT:N-N (domain,2)
MOD_ATT:N-N (domain,transcription)
MOD_ATT:N-N (domain,activation)
SUBJ:V_PASS-N (delete,domain)