In cell extract from liver of adult __SP__ , binding of a DNA fragment ( 124 96 ) containing a __NODE__ response element from __SP__ __NODE__ gene and __SP__ __NODE__ protein is greater than binding of a mutant DNA fragment ( 124 96 ) ( A?C A?C C?A A?T A?G ) containing a __NODE__ response element from __SP__ __NODE__ gene and __SP__ __NODE__ protein .