In cell free system , binding of a DNA fragment ( 5 ' GGGTTTGACCTTTCTCTCCGGGTAAAGGTGAAGG 3 ' containing a NRRE 1 from __SP__ __NODE__ gene and a protein protein complex consisting of __SP__ __NODE__ and of __SP__ __NODE__ is greater than binding of a mutant DNA fragment ( A?C C?T C?T ) ( 5 ' GGGTTTGCTTTTTCTCTCCGGGTAAAGGTGAAGG 3 ' containing a NRRE 1 from __SP__ __NODE__ gene and a protein protein complex consisting of __SP__ __NODE__ and of __SP__ __NODE__ .