In cell extract from liver of adult __SP__ , binding of a DNA fragment containing a __NODE__ response element from __SP__ __NODE__ gene and __SP__ __NODE__ protein is greater than binding of a mutant DNA fragment ( A 114G C 113T A 112C C 109T T 108A T 107A A 106T T 105C ) containing a __NODE__ response element from __SP__ __NODE__ gene and __SP__ __NODE__ protein .