In cell free system , binding of a DNA fragment ( TGACCCTTTTAACCAGGTCA ) containing a __NODE__ response element from __SP__ __NODE__ gene and heterodimer consisting of __NODE__ and of __NODE__ is greater than binding of a DNA fragment ( TGACCCTTTTAACCAGGTCA ) containing a __NODE__ response element from __SP__ __NODE__ gene and Rzr beta [__NODE__] protein .