In a cell free system , binding of a mutant DNA fragment ( 124 96 ) ( A 114G C 113T A 112C C 109T T 108A T 107A A 106T T 105C ) containing a __NODE__ response element from __SP__ __NODE__ gene and __SP__ __NODE__ protein is greater than or equal to binding of a mutant DNA fragment ( 124 96 ) ( C 113A A 112C T 108A T 107A T 105C ) containing a __NODE__ response element from __SP__ __NODE__ gene and __SP__ __NODE__ protein .