In a cell free system , binding of a DNA fragment ( TCGACTTCCAAAATGGGGATTAAATGAGGTAATATC ) from __SP__ __NODE__ gene and a protein protein complex consisting of __NODE__ and of __NODE__ is the same as binding of a DNA fragment ( TCGACTTCCAAAATGGGGATTACTTAAGGTAATATC ) from mutant __SP__ __NODE__ gene ( A?C A?T G?A ) and a protein protein complex consisting of __NODE__ and of __NODE__ .