In a cell free system , binding of a DNA fragment with a synthetic promoter that has a __NODE__ pregnane X response element 1 and a ER6 pregnane X response element from __SP__ __NODE__ gene and a protein protein complex consisting of __SP__ __NODE__ and of __SP__ __NODE__ is greater than binding of a DNA fragment with a synthetic promoter that has a __NODE__ pregnane X response element 1 from __SP__ __NODE__ gene and a protein protein complex consisting of __SP__ __NODE__ and of __SP__ __NODE__ .