In a cell free system , binding of a protein fragment ( 613 752 ) containing a LXXLL motif 1 ( aa sequence LLQLL ) and a LXXLL motif 2 ( aa sequence LHKLL ) and a mutant LXXLL motif 3 ( L740A L741A ) ( aa sequence LRYLL ) and a receptor binding domain from __NODE__ protein and __NODE__ protein is greater than binding of a protein fragment ( 613 752 ) containing a LXXLL motif 1 ( aa sequence LLQLL ) and a mutant LXXLL motif 2 ( L688A L689A ) ( aa sequence LHKLL ) and a LXXLL motif 3 ( aa sequence LRYLL ) and a receptor binding domain from __NODE__ protein and __NODE__ protein .